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- W2005012923 abstract "Beagles at the University of California at Davis injected with226 Ra or fed90 Sr have been under lifetime study for over 18 years. This report summarizes the dose-response observations to June 30, 1978, based upon the temporal average dose rate (rad/day) to the skeleton from initiation of exposure to death. Bone marrow dyscrasias were more numerous than bone cancers from90 Sr (in equilibrium with ${}^{90}{rm Y}$ ) at dose rates to bone of about 2 to 20 rad/day, while bone cancers have been the dominating effect of ${}^{226}{rm Ra}n$ (and associated progeny) at dose rates of from 0.5 to about 20 rad/day. No radiogenic effects are yet apparent for skeletal doses below 0.05 rad/day. Results to date indicate that although bone cancer continues to be the important endpoint for226 Ra, other cancer types appear to be more important for90 Sr (such as soft-tissue cancers adjacent to bone), particularly at late times from lower skeletal dose rates. Continued study of the 3..." @default.
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- W2005012923 date "1981-06-01" @default.
- W2005012923 modified "2023-09-26" @default.
- W2005012923 title "Lifetime Studies of 226 Ra and 90 Sr Toxicity in Beagles: A Status Report" @default.
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- W2005012923 doi "https://doi.org/10.2307/3575467" @default.
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