Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005016728> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2005016728 endingPage "79" @default.
- W2005016728 startingPage "75" @default.
- W2005016728 abstract "The mechanism of impairment of cytochrome P450 (P450)-dependent metabolism in hamster liver during leishmaniasis is reported. A significant decrease in the level of P450 was observed on the 20th day of infection when the parasite load in the liver was maximum. The decrease in P450 level was accompanied by a significant increase in the level of marker enzymes of liver and degeneration of liver tissue. The impairment was isozyme-specific and concomitant with the induction of nitric oxide synthase. The results of in vitro experiments with generated nitric oxide and with scavengers demonstrated that the impairment is mediated by NO. Treatment of the infected animals with a combination therapy showed reduction in parasite load, reversal of P450 impairment, and recovery of liver enzymes and tissue close to normal." @default.
- W2005016728 created "2016-06-24" @default.
- W2005016728 creator A5017275755 @default.
- W2005016728 creator A5031608480 @default.
- W2005016728 creator A5055377535 @default.
- W2005016728 creator A5063232962 @default.
- W2005016728 date "2003-12-01" @default.
- W2005016728 modified "2023-10-12" @default.
- W2005016728 title "Mechanism of impairment of cytochrome P450-dependent metabolism in hamster liver during leishmaniasis" @default.
- W2005016728 cites W1775749144 @default.
- W2005016728 cites W1951469402 @default.
- W2005016728 cites W1987418039 @default.
- W2005016728 cites W1988741013 @default.
- W2005016728 cites W1990802251 @default.
- W2005016728 cites W1993908745 @default.
- W2005016728 cites W1996421552 @default.
- W2005016728 cites W1997855734 @default.
- W2005016728 cites W2006998778 @default.
- W2005016728 cites W2035932547 @default.
- W2005016728 cites W2071016443 @default.
- W2005016728 cites W2074119648 @default.
- W2005016728 cites W2075200935 @default.
- W2005016728 cites W207591095 @default.
- W2005016728 cites W2087768842 @default.
- W2005016728 cites W2092517767 @default.
- W2005016728 cites W2100837269 @default.
- W2005016728 cites W2132927623 @default.
- W2005016728 cites W2263023695 @default.
- W2005016728 doi "https://doi.org/10.1016/j.bbrc.2003.09.227" @default.
- W2005016728 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14630021" @default.
- W2005016728 hasPublicationYear "2003" @default.
- W2005016728 type Work @default.
- W2005016728 sameAs 2005016728 @default.
- W2005016728 citedByCount "10" @default.
- W2005016728 countsByYear W20050167282012 @default.
- W2005016728 countsByYear W20050167282017 @default.
- W2005016728 countsByYear W20050167282021 @default.
- W2005016728 countsByYear W20050167282022 @default.
- W2005016728 crossrefType "journal-article" @default.
- W2005016728 hasAuthorship W2005016728A5017275755 @default.
- W2005016728 hasAuthorship W2005016728A5031608480 @default.
- W2005016728 hasAuthorship W2005016728A5055377535 @default.
- W2005016728 hasAuthorship W2005016728A5063232962 @default.
- W2005016728 hasConcept C119795356 @default.
- W2005016728 hasConcept C126322002 @default.
- W2005016728 hasConcept C134018914 @default.
- W2005016728 hasConcept C181199279 @default.
- W2005016728 hasConcept C2777622882 @default.
- W2005016728 hasConcept C2778575167 @default.
- W2005016728 hasConcept C519581460 @default.
- W2005016728 hasConcept C526171541 @default.
- W2005016728 hasConcept C55493867 @default.
- W2005016728 hasConcept C62231903 @default.
- W2005016728 hasConcept C71924100 @default.
- W2005016728 hasConcept C86803240 @default.
- W2005016728 hasConcept C89311334 @default.
- W2005016728 hasConcept C98274493 @default.
- W2005016728 hasConceptScore W2005016728C119795356 @default.
- W2005016728 hasConceptScore W2005016728C126322002 @default.
- W2005016728 hasConceptScore W2005016728C134018914 @default.
- W2005016728 hasConceptScore W2005016728C181199279 @default.
- W2005016728 hasConceptScore W2005016728C2777622882 @default.
- W2005016728 hasConceptScore W2005016728C2778575167 @default.
- W2005016728 hasConceptScore W2005016728C519581460 @default.
- W2005016728 hasConceptScore W2005016728C526171541 @default.
- W2005016728 hasConceptScore W2005016728C55493867 @default.
- W2005016728 hasConceptScore W2005016728C62231903 @default.
- W2005016728 hasConceptScore W2005016728C71924100 @default.
- W2005016728 hasConceptScore W2005016728C86803240 @default.
- W2005016728 hasConceptScore W2005016728C89311334 @default.
- W2005016728 hasConceptScore W2005016728C98274493 @default.
- W2005016728 hasIssue "1" @default.
- W2005016728 hasLocation W20050167281 @default.
- W2005016728 hasLocation W20050167282 @default.
- W2005016728 hasOpenAccess W2005016728 @default.
- W2005016728 hasPrimaryLocation W20050167281 @default.
- W2005016728 hasRelatedWork W2002452996 @default.
- W2005016728 hasRelatedWork W2024889190 @default.
- W2005016728 hasRelatedWork W2038976040 @default.
- W2005016728 hasRelatedWork W2079104442 @default.
- W2005016728 hasRelatedWork W2109737906 @default.
- W2005016728 hasRelatedWork W2120467119 @default.
- W2005016728 hasRelatedWork W2908779093 @default.
- W2005016728 hasRelatedWork W2949276520 @default.
- W2005016728 hasRelatedWork W3138676449 @default.
- W2005016728 hasRelatedWork W3216238012 @default.
- W2005016728 hasVolume "312" @default.
- W2005016728 isParatext "false" @default.
- W2005016728 isRetracted "false" @default.
- W2005016728 magId "2005016728" @default.
- W2005016728 workType "article" @default.