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• W2005019179 abstract "The magnetic resonance imaging (MRI) studies of controlled-release (CR) dosage forms can be roughly divided into two groups. The first comprises studies performed in static conditions (small solvent volumes and ambient temperature). Such studies have provided insight into molecular phenomena in hydrating polymeric matrices. The second group covers research performed in dynamic conditions (medium flow or stirring) related to drug dissolution. An important issue is supplementation of the MRI results with data obtained by complementary techniques, such as X-ray microtomography (μCT). As we discuss here, an understanding of the mechanism underlying the release of the drug from the dosage form will lead to the development of detailed, molecularly defined, CR dosage forms." @default.
• W2005019179 created "2016-06-24" @default.
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• W2005019179 date "2012-02-01" @default.
• W2005019179 modified "2023-09-25" @default.
• W2005019179 title "MRI as a tool for evaluation of oral controlled release dosage forms" @default.
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• W2005019179 doi "https://doi.org/10.1016/j.drudis.2011.10.026" @default.
• W2005019179 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22094243" @default.
• W2005019179 hasPublicationYear "2012" @default.
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