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- W2005019185 abstract "Aims Current guidelines for lipid lowering as primary prevention advocate a treatment threshold 10-year coronary heart disease (CHD) risk of ≥ 30%. There is a variety of methods of calculating CHD risk, of varying complexity, which incorporate different factors. We aimed to determine if different methods of CHD risk calculation give different results and if a simpler method of CHD risk calculation could be developed for type 2 diabetes. Methods Using three recognised methods based on the Framingham equation, CHD risk was calculated for 200 consecutive patients with type 2 diabetes attending the clinic. A simple method of establishing those who should be treated with lipid-lowering agents was developed and sensitivity and specificity compared to the established method. Results Using method 1, only 58 (29%) of the patients would be above the treatment threshold; 108 (54%) with method 2; and 140 (70%) with method 3 ( 2 =68.3, p < 0.001). Using the Glasgow Chart, sensitivity and specificity would be 100% and 85% respectively if patients are identified with total cholesterol ≥ 5.0 mmol/L plus two of: 1) age ≥ 50 years; 2) blood pressure ≥ 140/80 mmHg; 3) microalbuminuria. Conclusions It makes a significant difference which method is used to calculate CHD risk. Our simple method seems to be applicable to patients with type 2 diabetes, but requires confirmation in a larger population." @default.
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- W2005019185 date "2002-05-01" @default.
- W2005019185 modified "2023-09-23" @default.
- W2005019185 title "The Glasgow Chart — a simple method for calculation of cardiovascular risk in type 2 diabetes" @default.
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- W2005019185 doi "https://doi.org/10.1177/14746514020020031201" @default.
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