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- W2005027567 abstract "The authors present the first case of a pure osteosarcoma arising in a long-standing uterine leiomyoma along with a literature review of all heterologous sarcomas arising in uterine leiomyoma. Most cases present with abnormal vaginal bleeding and symptoms related to a rapidly enlarged pelvic mass in postmenopausal women with a long-standing history of uterine leiomyoma. The histological finding of the case in this study revealed a relatively well-circumscribed tumor with a peripheral ring of leiomyoma and a central osteosarcoma. The case in this study further supported a possible pathogenesis involving the p53 gene. The prognosis may be better with low-stage tumor; however, cases with advanced stages, larger tumor size at presentation, and histological type of epithelioid angiosarcoma had poorer prognosis despite aggressive therapy." @default.
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- W2005027567 date "2008-11-17" @default.
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- W2005027567 title "Osteosarcoma Arising in a Long-Standing Uterine Leiomyoma: A Case Report and Literature Review" @default.
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- W2005027567 doi "https://doi.org/10.1177/1066896908327037" @default.
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