FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005059020> ?p ?o ?g. }

• W2005059020 endingPage "136" @default.
• W2005059020 startingPage "129" @default.
• W2005059020 abstract "We have characterized the reactivities of a panel of V4‐34‐encoded human IgM monoclonal antibodies (mAb) which bind the erythrocyte Rh D antigen, derived from an immunized individual. These were compared with the specificities of V4‐34‐encoded autoantibodies with I/i reactivity produced from patients with cold agglutinin disease (CAD), and other V4‐34‐encoded autoantibodies. The antibodies were evaluated for cold agglutinin activity using haemagglutination tests, immunofluorescence microscopy for reactivity with tissue components, and in solid phase radiobinding assays with purified antigens. We found that (i) cold agglutinin activity was a property of all the V4‐34‐encoded mAb (ii) the cold agglutinins from CAD patients were generally monospecific for I/i whereas most of the anti‐D and the other V4‐34‐encoded mAb displayed multireactive properties, frequently binding to strongly acidic antigens (iii) computation of the net charge of the heavy‐chain V regions showed that the multireactive mAb were generally more positively charged than the monospecific cold agglutinins, which could contribute to their multireactive phenotype. The involvement of charge interactions was further indicated by the effects of pH and ionic strength on the immunofluorescence staining patterns." @default.
• W2005059020 created "2016-06-24" @default.
• W2005059020 creator A5000560776 @default.
• W2005059020 creator A5013830579 @default.
• W2005059020 creator A5015208014 @default.
• W2005059020 creator A5047140412 @default.
• W2005059020 creator A5063567071 @default.
• W2005059020 creator A5084929088 @default.
• W2005059020 creator A5089836894 @default.
• W2005059020 date "1998-01-01" @default.
• W2005059020 modified "2023-09-23" @default.
• W2005059020 title "Human monoclonal antibodies encoded by the V4‐34 gene segment show cold agglutinin activity and variable multireactivity which correlates with the predicted charge of the heavy‐chain variable region" @default.
• W2005059020 cites W1515850288 @default.
• W2005059020 cites W1516236635 @default.
• W2005059020 cites W1525618611 @default.
• W2005059020 cites W1574482841 @default.
• W2005059020 cites W1590558272 @default.
• W2005059020 cites W1964503791 @default.
• W2005059020 cites W1983100355 @default.
• W2005059020 cites W1995106958 @default.
• W2005059020 cites W2006243118 @default.
• W2005059020 cites W2020897056 @default.
• W2005059020 cites W204107356 @default.
• W2005059020 cites W2069978006 @default.
• W2005059020 cites W2072889133 @default.
• W2005059020 cites W2074560324 @default.
• W2005059020 cites W2075910826 @default.
• W2005059020 cites W2087789563 @default.
• W2005059020 cites W2090127720 @default.
• W2005059020 cites W2091439945 @default.
• W2005059020 cites W2103974219 @default.
• W2005059020 cites W2272388427 @default.
• W2005059020 cites W2397491210 @default.
• W2005059020 cites W2398726495 @default.
• W2005059020 cites W2411421886 @default.
• W2005059020 cites W69898101 @default.
• W2005059020 cites W73223263 @default.
• W2005059020 doi "https://doi.org/10.1046/j.1365-2567.1998.00406.x" @default.
• W2005059020 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1364116" @default.
• W2005059020 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9536129" @default.
• W2005059020 hasPublicationYear "1998" @default.
• W2005059020 type Work @default.
• W2005059020 sameAs 2005059020 @default.
• W2005059020 citedByCount "31" @default.
• W2005059020 countsByYear W20050590202013 @default.
• W2005059020 countsByYear W20050590202015 @default.
• W2005059020 countsByYear W20050590202022 @default.
• W2005059020 crossrefType "journal-article" @default.
• W2005059020 hasAuthorship W2005059020A5000560776 @default.
• W2005059020 hasAuthorship W2005059020A5013830579 @default.
• W2005059020 hasAuthorship W2005059020A5015208014 @default.
• W2005059020 hasAuthorship W2005059020A5047140412 @default.
• W2005059020 hasAuthorship W2005059020A5063567071 @default.
• W2005059020 hasAuthorship W2005059020A5084929088 @default.
• W2005059020 hasAuthorship W2005059020A5089836894 @default.
• W2005059020 hasBestOaLocation W20050590201 @default.
• W2005059020 hasConcept C147483822 @default.
• W2005059020 hasConcept C153911025 @default.
• W2005059020 hasConcept C159654299 @default.
• W2005059020 hasConcept C163764329 @default.
• W2005059020 hasConcept C163864487 @default.
• W2005059020 hasConcept C185592680 @default.
• W2005059020 hasConcept C203014093 @default.
• W2005059020 hasConcept C207545495 @default.
• W2005059020 hasConcept C2777884830 @default.
• W2005059020 hasConcept C2778236600 @default.
• W2005059020 hasConcept C2780758401 @default.
• W2005059020 hasConcept C2910849039 @default.
• W2005059020 hasConcept C34343649 @default.
• W2005059020 hasConcept C542903549 @default.
• W2005059020 hasConcept C86803240 @default.
• W2005059020 hasConceptScore W2005059020C147483822 @default.
• W2005059020 hasConceptScore W2005059020C153911025 @default.
• W2005059020 hasConceptScore W2005059020C159654299 @default.
• W2005059020 hasConceptScore W2005059020C163764329 @default.
• W2005059020 hasConceptScore W2005059020C163864487 @default.
• W2005059020 hasConceptScore W2005059020C185592680 @default.
• W2005059020 hasConceptScore W2005059020C203014093 @default.
• W2005059020 hasConceptScore W2005059020C207545495 @default.
• W2005059020 hasConceptScore W2005059020C2777884830 @default.
• W2005059020 hasConceptScore W2005059020C2778236600 @default.
• W2005059020 hasConceptScore W2005059020C2780758401 @default.
• W2005059020 hasConceptScore W2005059020C2910849039 @default.
• W2005059020 hasConceptScore W2005059020C34343649 @default.
• W2005059020 hasConceptScore W2005059020C542903549 @default.
• W2005059020 hasConceptScore W2005059020C86803240 @default.
• W2005059020 hasIssue "1" @default.
• W2005059020 hasLocation W20050590201 @default.
• W2005059020 hasLocation W20050590202 @default.
• W2005059020 hasLocation W20050590203 @default.
• W2005059020 hasOpenAccess W2005059020 @default.
• W2005059020 hasPrimaryLocation W20050590201 @default.
• W2005059020 hasRelatedWork W178914116 @default.
• W2005059020 hasRelatedWork W1997716688 @default.
• W2005059020 hasRelatedWork W2005059020 @default.
• W2005059020 hasRelatedWork W2037509311 @default.
• W2005059020 hasRelatedWork W2048939492 @default.
• W2005059020 hasRelatedWork W2071136098 @default.

• next