FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005059632> ?p ?o ?g. }

• W2005059632 endingPage "834" @default.
• W2005059632 startingPage "829" @default.
• W2005059632 abstract "Whether in vitro antifungal susceptibility findings correlate with the outcome of patients with invasive aspergillosis (IA) remains debated. This study aimed to test whether IA patients’ outcomes were associated with in vitro susceptibility results. To do so, we determined the in vitro susceptibility to amphotericin B (AMB) of 37 Aspergillus flavus isolates from 14 patients with haematological malignancies diagnosed with proven or probable IA, of which 13 were treated with AMB deoxycholate. Minimal inhibitory concentrations (MICs) were determined by Etest with the isolates classified as in vitro sensitive (AMB-S) or resistant (AMB-R) if their MICs were < 2 or ≥ 2 mg/l, respectively. The association of the patients’ death with primary disease, administered antifungal treatment, and infection with AMB-R A. flavus was tested using generalized estimating equations logistic regression. We assessed AMB-R in 31/37 (84%) isolates. In the patients treated with AMB, the survival rate was 2/3 (67%) and 2/9 (22%) for those infected with AMB-S or AMB-R A. flavus, respectively. Both infection with AMB-R A. flavus (P = 0.014) strain and acute myelocytic leukaemia as the underlying primary disease (P = 0.036) were independent predictors of death. Our findings indicate that in vitro resistance predicts a poor outcome in patients with A. flavus invasive disease treated with AMB. Recent advances in non-culture-based microbiological methods should not discourage efforts to obtain in vitro antifungal susceptibility results, which are critical for the choice of antifungal therapy in patients with IA." @default.
• W2005059632 created "2016-06-24" @default.
• W2005059632 creator A5001001765 @default.
• W2005059632 creator A5004004478 @default.
• W2005059632 creator A5020692401 @default.
• W2005059632 creator A5039346412 @default.
• W2005059632 creator A5051956051 @default.
• W2005059632 creator A5065737087 @default.
• W2005059632 creator A5070809955 @default.
• W2005059632 creator A5090461600 @default.
• W2005059632 date "2012-11-01" @default.
• W2005059632 modified "2023-10-03" @default.
• W2005059632 title "Amphotericin B<i>in vitro</i>resistance is associated with fatal<i>Aspergillus flavus</i>infection" @default.
• W2005059632 cites W1819112229 @default.
• W2005059632 cites W1938704097 @default.
• W2005059632 cites W1979793660 @default.
• W2005059632 cites W1992056414 @default.
• W2005059632 cites W2042018562 @default.
• W2005059632 cites W2047133769 @default.
• W2005059632 cites W2057425442 @default.
• W2005059632 cites W2065148635 @default.
• W2005059632 cites W2066421491 @default.
• W2005059632 cites W2097076008 @default.
• W2005059632 cites W2112175944 @default.
• W2005059632 cites W2113237293 @default.
• W2005059632 cites W2118836068 @default.
• W2005059632 cites W2131778095 @default.
• W2005059632 cites W2137344994 @default.
• W2005059632 cites W2138498905 @default.
• W2005059632 cites W2144918204 @default.
• W2005059632 cites W2149220964 @default.
• W2005059632 cites W2149546447 @default.
• W2005059632 cites W2156836029 @default.
• W2005059632 cites W2160867136 @default.
• W2005059632 cites W2166734004 @default.
• W2005059632 cites W2167817685 @default.
• W2005059632 doi "https://doi.org/10.3109/13693786.2012.684154" @default.
• W2005059632 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22587728" @default.
• W2005059632 hasPublicationYear "2012" @default.
• W2005059632 type Work @default.
• W2005059632 sameAs 2005059632 @default.
• W2005059632 citedByCount "39" @default.
• W2005059632 countsByYear W20050596322012 @default.
• W2005059632 countsByYear W20050596322013 @default.
• W2005059632 countsByYear W20050596322014 @default.
• W2005059632 countsByYear W20050596322015 @default.
• W2005059632 countsByYear W20050596322016 @default.
• W2005059632 countsByYear W20050596322017 @default.
• W2005059632 countsByYear W20050596322018 @default.
• W2005059632 countsByYear W20050596322019 @default.
• W2005059632 countsByYear W20050596322020 @default.
• W2005059632 countsByYear W20050596322021 @default.
• W2005059632 countsByYear W20050596322022 @default.
• W2005059632 countsByYear W20050596322023 @default.
• W2005059632 crossrefType "journal-article" @default.
• W2005059632 hasAuthorship W2005059632A5001001765 @default.
• W2005059632 hasAuthorship W2005059632A5004004478 @default.
• W2005059632 hasAuthorship W2005059632A5020692401 @default.
• W2005059632 hasAuthorship W2005059632A5039346412 @default.
• W2005059632 hasAuthorship W2005059632A5051956051 @default.
• W2005059632 hasAuthorship W2005059632A5065737087 @default.
• W2005059632 hasAuthorship W2005059632A5070809955 @default.
• W2005059632 hasAuthorship W2005059632A5090461600 @default.
• W2005059632 hasBestOaLocation W20050596321 @default.
• W2005059632 hasConcept C126322002 @default.
• W2005059632 hasConcept C176947019 @default.
• W2005059632 hasConcept C202751555 @default.
• W2005059632 hasConcept C203014093 @default.
• W2005059632 hasConcept C2776391196 @default.
• W2005059632 hasConcept C2777292910 @default.
• W2005059632 hasConcept C2779548794 @default.
• W2005059632 hasConcept C2779629538 @default.
• W2005059632 hasConcept C2780908437 @default.
• W2005059632 hasConcept C501593827 @default.
• W2005059632 hasConcept C55493867 @default.
• W2005059632 hasConcept C71924100 @default.
• W2005059632 hasConcept C81396022 @default.
• W2005059632 hasConcept C86803240 @default.
• W2005059632 hasConcept C89423630 @default.
• W2005059632 hasConceptScore W2005059632C126322002 @default.
• W2005059632 hasConceptScore W2005059632C176947019 @default.
• W2005059632 hasConceptScore W2005059632C202751555 @default.
• W2005059632 hasConceptScore W2005059632C203014093 @default.
• W2005059632 hasConceptScore W2005059632C2776391196 @default.
• W2005059632 hasConceptScore W2005059632C2777292910 @default.
• W2005059632 hasConceptScore W2005059632C2779548794 @default.
• W2005059632 hasConceptScore W2005059632C2779629538 @default.
• W2005059632 hasConceptScore W2005059632C2780908437 @default.
• W2005059632 hasConceptScore W2005059632C501593827 @default.
• W2005059632 hasConceptScore W2005059632C55493867 @default.
• W2005059632 hasConceptScore W2005059632C71924100 @default.
• W2005059632 hasConceptScore W2005059632C81396022 @default.
• W2005059632 hasConceptScore W2005059632C86803240 @default.
• W2005059632 hasConceptScore W2005059632C89423630 @default.
• W2005059632 hasIssue "8" @default.
• W2005059632 hasLocation W20050596321 @default.
• W2005059632 hasLocation W20050596322 @default.
• W2005059632 hasOpenAccess W2005059632 @default.

• next