Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005081246> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2005081246 endingPage "19" @default.
- W2005081246 startingPage "10" @default.
- W2005081246 abstract "Prostatic intraepithelial neoplasia (PIN) represents the putative precancerous end of the morphologic continuum of cellular proliferations within prostatic ducts, ductules an acini. Two grades of PIN are identified (low grade and high grade), and high grade PIN is considered to be a precursor to invasive carcinoma. The continuum which culminates in high grade PIN and early invasive cancer is characterized by basal cell layer disruption, basement membrane disruption, progressive loss of secretory differentiation markers, increasing nuclear and nucleolar abnormalities, increasing proliferative potential, and increasing variation in DNA content (aneuploidy). Clinical studies suggest that PIN predates carcinoma by ten years or more, with low grade PIN first emerging in men in the third decade of life. The clinical importance of recognizing PIN is based on its strong association with carcinoma; its identification in biopsy specimens of the prostate warrants further search for concurrent invasive carcinoma. © 1992 Wiley-Liss, Inc." @default.
- W2005081246 created "2016-06-24" @default.
- W2005081246 creator A5048482314 @default.
- W2005081246 date "1992-01-01" @default.
- W2005081246 modified "2023-10-16" @default.
- W2005081246 title "Prostatic intraepithelial neoplasia (PIN): Current concepts" @default.
- W2005081246 cites W1500424486 @default.
- W2005081246 cites W1508662384 @default.
- W2005081246 cites W1980977659 @default.
- W2005081246 cites W1983712904 @default.
- W2005081246 cites W1985438891 @default.
- W2005081246 cites W2001073980 @default.
- W2005081246 cites W2003851518 @default.
- W2005081246 cites W2013217410 @default.
- W2005081246 cites W2063905655 @default.
- W2005081246 cites W2065479209 @default.
- W2005081246 cites W2077409718 @default.
- W2005081246 cites W2084197013 @default.
- W2005081246 cites W2101000333 @default.
- W2005081246 cites W2157104106 @default.
- W2005081246 cites W2267247859 @default.
- W2005081246 cites W2322348418 @default.
- W2005081246 cites W2326379396 @default.
- W2005081246 cites W2334696277 @default.
- W2005081246 cites W52017653 @default.
- W2005081246 doi "https://doi.org/10.1002/jcb.240501205" @default.
- W2005081246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1289664" @default.
- W2005081246 hasPublicationYear "1992" @default.
- W2005081246 type Work @default.
- W2005081246 sameAs 2005081246 @default.
- W2005081246 citedByCount "100" @default.
- W2005081246 countsByYear W20050812462012 @default.
- W2005081246 countsByYear W20050812462013 @default.
- W2005081246 countsByYear W20050812462014 @default.
- W2005081246 countsByYear W20050812462015 @default.
- W2005081246 countsByYear W20050812462017 @default.
- W2005081246 countsByYear W20050812462020 @default.
- W2005081246 countsByYear W20050812462021 @default.
- W2005081246 crossrefType "journal-article" @default.
- W2005081246 hasAuthorship W2005081246A5048482314 @default.
- W2005081246 hasConcept C121608353 @default.
- W2005081246 hasConcept C126322002 @default.
- W2005081246 hasConcept C142724271 @default.
- W2005081246 hasConcept C2775934546 @default.
- W2005081246 hasConcept C2776193487 @default.
- W2005081246 hasConcept C2776235491 @default.
- W2005081246 hasConcept C2776456063 @default.
- W2005081246 hasConcept C2777546739 @default.
- W2005081246 hasConcept C2779534503 @default.
- W2005081246 hasConcept C2780192828 @default.
- W2005081246 hasConcept C502942594 @default.
- W2005081246 hasConcept C71924100 @default.
- W2005081246 hasConcept C86803240 @default.
- W2005081246 hasConceptScore W2005081246C121608353 @default.
- W2005081246 hasConceptScore W2005081246C126322002 @default.
- W2005081246 hasConceptScore W2005081246C142724271 @default.
- W2005081246 hasConceptScore W2005081246C2775934546 @default.
- W2005081246 hasConceptScore W2005081246C2776193487 @default.
- W2005081246 hasConceptScore W2005081246C2776235491 @default.
- W2005081246 hasConceptScore W2005081246C2776456063 @default.
- W2005081246 hasConceptScore W2005081246C2777546739 @default.
- W2005081246 hasConceptScore W2005081246C2779534503 @default.
- W2005081246 hasConceptScore W2005081246C2780192828 @default.
- W2005081246 hasConceptScore W2005081246C502942594 @default.
- W2005081246 hasConceptScore W2005081246C71924100 @default.
- W2005081246 hasConceptScore W2005081246C86803240 @default.
- W2005081246 hasIssue "S16H" @default.
- W2005081246 hasLocation W20050812461 @default.
- W2005081246 hasLocation W20050812462 @default.
- W2005081246 hasOpenAccess W2005081246 @default.
- W2005081246 hasPrimaryLocation W20050812461 @default.
- W2005081246 hasRelatedWork W1818826284 @default.
- W2005081246 hasRelatedWork W2019340165 @default.
- W2005081246 hasRelatedWork W2028329711 @default.
- W2005081246 hasRelatedWork W2046438699 @default.
- W2005081246 hasRelatedWork W2073543802 @default.
- W2005081246 hasRelatedWork W2126559236 @default.
- W2005081246 hasRelatedWork W2169738785 @default.
- W2005081246 hasRelatedWork W2397934522 @default.
- W2005081246 hasRelatedWork W2803198186 @default.
- W2005081246 hasRelatedWork W4200628798 @default.
- W2005081246 hasVolume "50" @default.
- W2005081246 isParatext "false" @default.
- W2005081246 isRetracted "false" @default.
- W2005081246 magId "2005081246" @default.
- W2005081246 workType "article" @default.