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- W2005096208 abstract "A simple paper chromatographic test of skin homogenates has been devised as an indirect method of detecting the enzyme defect in histidinemia. The test optimally utilized lized 1 to 2 mg. of stratum corneum but can be performed on as little as 0.5 mg. of this tissue. This small amount of skin is easily obtainable from infants and children, in contrast to the much larger amounts of skin necessary for the direct histidase assay. All nonhistidinemic persons tested (113) had clearly visible urocanic acid in skin, whereas none of the 7 histidinemic persons tested had any visible urocanic acid. Heterozygotes for histidinemia could not be differentiated from normal persons by this test." @default.
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- W2005096208 title "A simple indirect method of detecting the enzyme defect in histidinemia" @default.
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- W2005096208 doi "https://doi.org/10.1016/s0022-3476(69)80348-3" @default.
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