Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005132487> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2005132487 abstract "Perinuclear antineutrophil cytoplasmic antibodies (ANCA) have been reported in patients and relatives of patients with ulcerative colitis and primary sclerosing cholangitis, suggesting that ANCA may be a genetic marker of disease susceptibility. The reported frequency of ANCA in relatives has varied greatly, between 0 and 30%. We therefore studied the prevalence of ANCA in unaffected first-degree relatives of British patients with primary sclerosing cholangitis and ulcerative colitis.Thirty-six patients with ulcerative colitis, 33 with primary sclerosing cholangitis and 187 relatives were studied. Ninety-seven relatives were from the primary sclerosing cholangitis proband and 90 were from the ulcerative colitis proband. As an environmental control, 32 spouses were included: 14 from the primary sclerosing cholangitis group and 18 from the ulcerative colitis group. Eighteen healthy volunteers were additional controls.ANCA was detected using immunoalkaline phosphatase method.Only 3 of 97 (3%) of the primary sclerosing cholangitis proband relatives had ANCA. One of these had ulcerative colitis, one had rheumatoid arthritis and the third systemic lupus erythematosus. Both rheumatoid arthritis and system lupus erythematosus are known to exhibit ANCA. All other sera were negative.ANCA was found only in patients with primary cholangitis and ulcerative colitis and not in their healthy first-degree relatives. ANCA is therefore not a genetic marker for increased disease susceptibility to primary sclerosing cholangitis or ulcerative colitis in the British population." @default.
- W2005132487 created "2016-06-24" @default.
- W2005132487 creator A5024812324 @default.
- W2005132487 creator A5027956350 @default.
- W2005132487 creator A5035673731 @default.
- W2005132487 creator A5055878854 @default.
- W2005132487 date "1996-02-01" @default.
- W2005132487 modified "2023-09-26" @default.
- W2005132487 title "Absence of antineutrophil cytoplasmic antibodies in relatives of UK patients with primary sclerosing cholangitis and ulcerative colitis" @default.
- W2005132487 doi "https://doi.org/10.1097/00042737-199602000-00004" @default.
- W2005132487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8723413" @default.
- W2005132487 hasPublicationYear "1996" @default.
- W2005132487 type Work @default.
- W2005132487 sameAs 2005132487 @default.
- W2005132487 citedByCount "28" @default.
- W2005132487 countsByYear W20051324872012 @default.
- W2005132487 countsByYear W20051324872013 @default.
- W2005132487 crossrefType "journal-article" @default.
- W2005132487 hasAuthorship W2005132487A5024812324 @default.
- W2005132487 hasAuthorship W2005132487A5027956350 @default.
- W2005132487 hasAuthorship W2005132487A5035673731 @default.
- W2005132487 hasAuthorship W2005132487A5055878854 @default.
- W2005132487 hasConcept C104317684 @default.
- W2005132487 hasConcept C126322002 @default.
- W2005132487 hasConcept C185592680 @default.
- W2005132487 hasConcept C188997412 @default.
- W2005132487 hasConcept C203014093 @default.
- W2005132487 hasConcept C24040308 @default.
- W2005132487 hasConcept C2776015282 @default.
- W2005132487 hasConcept C2777575956 @default.
- W2005132487 hasConcept C2778260677 @default.
- W2005132487 hasConcept C2779134260 @default.
- W2005132487 hasConcept C2780479503 @default.
- W2005132487 hasConcept C2780615123 @default.
- W2005132487 hasConcept C2908647359 @default.
- W2005132487 hasConcept C501734568 @default.
- W2005132487 hasConcept C55493867 @default.
- W2005132487 hasConcept C71924100 @default.
- W2005132487 hasConcept C90924648 @default.
- W2005132487 hasConcept C99454951 @default.
- W2005132487 hasConceptScore W2005132487C104317684 @default.
- W2005132487 hasConceptScore W2005132487C126322002 @default.
- W2005132487 hasConceptScore W2005132487C185592680 @default.
- W2005132487 hasConceptScore W2005132487C188997412 @default.
- W2005132487 hasConceptScore W2005132487C203014093 @default.
- W2005132487 hasConceptScore W2005132487C24040308 @default.
- W2005132487 hasConceptScore W2005132487C2776015282 @default.
- W2005132487 hasConceptScore W2005132487C2777575956 @default.
- W2005132487 hasConceptScore W2005132487C2778260677 @default.
- W2005132487 hasConceptScore W2005132487C2779134260 @default.
- W2005132487 hasConceptScore W2005132487C2780479503 @default.
- W2005132487 hasConceptScore W2005132487C2780615123 @default.
- W2005132487 hasConceptScore W2005132487C2908647359 @default.
- W2005132487 hasConceptScore W2005132487C501734568 @default.
- W2005132487 hasConceptScore W2005132487C55493867 @default.
- W2005132487 hasConceptScore W2005132487C71924100 @default.
- W2005132487 hasConceptScore W2005132487C90924648 @default.
- W2005132487 hasConceptScore W2005132487C99454951 @default.
- W2005132487 hasLocation W20051324871 @default.
- W2005132487 hasLocation W20051324872 @default.
- W2005132487 hasOpenAccess W2005132487 @default.
- W2005132487 hasPrimaryLocation W20051324871 @default.
- W2005132487 hasRelatedWork W1745867474 @default.
- W2005132487 hasRelatedWork W2009448977 @default.
- W2005132487 hasRelatedWork W2069027651 @default.
- W2005132487 hasRelatedWork W2086360535 @default.
- W2005132487 hasRelatedWork W2087953398 @default.
- W2005132487 hasRelatedWork W2381649008 @default.
- W2005132487 hasRelatedWork W2414225138 @default.
- W2005132487 hasRelatedWork W2467986563 @default.
- W2005132487 hasRelatedWork W3027335955 @default.
- W2005132487 hasRelatedWork W4200230788 @default.
- W2005132487 isParatext "false" @default.
- W2005132487 isRetracted "false" @default.
- W2005132487 magId "2005132487" @default.
- W2005132487 workType "article" @default.