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- W2005141041 abstract "A unit-dose oral vitamin K1 solution (1 mg ml-1), was developed for administration to neonates as prophylaxis against early haemorrhagic disease of the new-born. Previously, a multidose oral-drop solution was prepared from sterile ampoules of vitamin K1 injection (10mg ml-1) The unit-dose preparation enabled accurate and convenient dose delivery and was more economical than the multidose solution. Furthermore, the preparation of sterile, single-dose units enabled the elimination of potentially harmful preservatives from the formulation. The unit-dose preparation was shown to be stable for 6 months under refrigerated storage conditions." @default.
- W2005141041 created "2016-06-24" @default.
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- W2005141041 date "1988-02-01" @default.
- W2005141041 modified "2023-09-23" @default.
- W2005141041 title "THE FORMULATION AND STABILITY OF A UNIT-DOSE ORAL VITAMIN K<sub>1</sub>PREPARATION" @default.
- W2005141041 cites W1965178188 @default.
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- W2005141041 doi "https://doi.org/10.1111/j.1365-2710.1988.tb00508.x" @default.
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