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- W2005156700 abstract "Circulating endothelial cells (CECs) have been put forward as a promising biomarker for diagnosis and prognosis of coronary artery disease and acute coronary syndromes. This review entails current insights into the physiology and pathobiology of CECs, including their relationship with circulating endothelial progenitor cells and endothelial microparticles. Additionally, we present a comprehensive overview of the diagnostic and prognostic value of CEC quantification, as well as possibilities for improvement, for example, by inclusion of CEC morphology, transcriptomics, and proteomics. The current stand of knowledge calls out for improved counting methods and consensus on a validated cell definition. Finally, our review accentuates the importance of large, well-designed, population-based prospective studies that will have to show the clinical value of CEC as a cardiovascular biomarker." @default.
- W2005156700 created "2016-06-24" @default.
- W2005156700 creator A5062206583 @default.
- W2005156700 creator A5067234996 @default.
- W2005156700 creator A5074307769 @default.
- W2005156700 date "2015-10-01" @default.
- W2005156700 modified "2023-09-30" @default.
- W2005156700 title "Circulating endothelial cells in coronary artery disease and acute coronary syndrome" @default.
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- W2005156700 doi "https://doi.org/10.1016/j.tcm.2015.01.013" @default.
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