Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005163069> ?p ?o ?g. }
- W2005163069 endingPage "225" @default.
- W2005163069 startingPage "217" @default.
- W2005163069 abstract "Purpose The current study analyzes the potential role of radiotherapy (RT) in symptomatic vertebral hemangioma (SVH). Methods and Materials Seven cooperating German institutions collected clinical information, treatment plans, and outcome data for all patients with SVH referred for local RT. Results From 1969 to 2008, a total of 84 patients with 96 symptomatic lesions were irradiated for SVH. The primary indication for radiotherapy was pain (97.6%), and 28.6% of patients had additional neurological symptoms. RT was performed at a median total dose of 34 Gy, with a median single dose of 2.0 Gy. After receiving a median follow-up of 68 months, the overall patient response rate was 90.5%. Complete symptom remission occurred in 61.9% of patients, 28.6% of patients had partial pain relief, and 9.5% of patients had no pain relief. In 26.2% of patients, radiological signs of reossification were observed in long-term follow-up but not significantly correlated with pain relief. Most importantly, total doses of ≥34 Gy resulted in significantly greater symptomatic relief and control rate than total doses of <34 Gy. Conclusions This study consists of the largest database of cases reported so far using RT for SVH. RT is easy, safe, and effective for pain relief treatment for SVH. Total doses of at least 34 Gy give the best symptomatic response. The current study analyzes the potential role of radiotherapy (RT) in symptomatic vertebral hemangioma (SVH). Seven cooperating German institutions collected clinical information, treatment plans, and outcome data for all patients with SVH referred for local RT. From 1969 to 2008, a total of 84 patients with 96 symptomatic lesions were irradiated for SVH. The primary indication for radiotherapy was pain (97.6%), and 28.6% of patients had additional neurological symptoms. RT was performed at a median total dose of 34 Gy, with a median single dose of 2.0 Gy. After receiving a median follow-up of 68 months, the overall patient response rate was 90.5%. Complete symptom remission occurred in 61.9% of patients, 28.6% of patients had partial pain relief, and 9.5% of patients had no pain relief. In 26.2% of patients, radiological signs of reossification were observed in long-term follow-up but not significantly correlated with pain relief. Most importantly, total doses of ≥34 Gy resulted in significantly greater symptomatic relief and control rate than total doses of <34 Gy. This study consists of the largest database of cases reported so far using RT for SVH. RT is easy, safe, and effective for pain relief treatment for SVH. Total doses of at least 34 Gy give the best symptomatic response." @default.
- W2005163069 created "2016-06-24" @default.
- W2005163069 creator A5005634016 @default.
- W2005163069 creator A5005873321 @default.
- W2005163069 creator A5018159826 @default.
- W2005163069 creator A5036914319 @default.
- W2005163069 creator A5040858567 @default.
- W2005163069 creator A5047995724 @default.
- W2005163069 creator A5057206849 @default.
- W2005163069 creator A5083161940 @default.
- W2005163069 creator A5085866807 @default.
- W2005163069 date "2010-05-01" @default.
- W2005163069 modified "2023-10-18" @default.
- W2005163069 title "Radiotherapy for Symptomatic Vertebral Hemangiomas: Results of a Multicenter Study and Literature Review" @default.
- W2005163069 cites W135684214 @default.
- W2005163069 cites W1514736380 @default.
- W2005163069 cites W1547816064 @default.
- W2005163069 cites W1964023129 @default.
- W2005163069 cites W1966142536 @default.
- W2005163069 cites W1966829959 @default.
- W2005163069 cites W1967232324 @default.
- W2005163069 cites W1967908846 @default.
- W2005163069 cites W1969596390 @default.
- W2005163069 cites W1976979119 @default.
- W2005163069 cites W1985560918 @default.
- W2005163069 cites W1985636919 @default.
- W2005163069 cites W1985749829 @default.
- W2005163069 cites W1989711768 @default.
- W2005163069 cites W1996157766 @default.
- W2005163069 cites W2003197130 @default.
- W2005163069 cites W2007634884 @default.
- W2005163069 cites W2007693416 @default.
- W2005163069 cites W2011072914 @default.
- W2005163069 cites W2011814079 @default.
- W2005163069 cites W2012664280 @default.
- W2005163069 cites W2013089994 @default.
- W2005163069 cites W2013487520 @default.
- W2005163069 cites W2019532247 @default.
- W2005163069 cites W2022707801 @default.
- W2005163069 cites W2024390764 @default.
- W2005163069 cites W2028598834 @default.
- W2005163069 cites W2034788787 @default.
- W2005163069 cites W2036988444 @default.
- W2005163069 cites W2038753851 @default.
- W2005163069 cites W2045434974 @default.
- W2005163069 cites W2052961317 @default.
- W2005163069 cites W2059031292 @default.
- W2005163069 cites W2063465167 @default.
- W2005163069 cites W2066405213 @default.
- W2005163069 cites W2066721312 @default.
- W2005163069 cites W2069831997 @default.
- W2005163069 cites W2070799077 @default.
- W2005163069 cites W2071303567 @default.
- W2005163069 cites W2074026991 @default.
- W2005163069 cites W2077865285 @default.
- W2005163069 cites W2079908159 @default.
- W2005163069 cites W2080396606 @default.
- W2005163069 cites W2081972629 @default.
- W2005163069 cites W2084759401 @default.
- W2005163069 cites W2089413314 @default.
- W2005163069 cites W2101948722 @default.
- W2005163069 cites W2102653712 @default.
- W2005163069 cites W2119649446 @default.
- W2005163069 cites W2120875582 @default.
- W2005163069 cites W2121694626 @default.
- W2005163069 cites W2125686177 @default.
- W2005163069 cites W2131580208 @default.
- W2005163069 cites W2132026729 @default.
- W2005163069 cites W2133225587 @default.
- W2005163069 cites W2137060012 @default.
- W2005163069 cites W2139022549 @default.
- W2005163069 cites W2144304897 @default.
- W2005163069 cites W2159199349 @default.
- W2005163069 cites W2259688682 @default.
- W2005163069 cites W2324306988 @default.
- W2005163069 cites W2411009938 @default.
- W2005163069 cites W2474382620 @default.
- W2005163069 cites W2887215874 @default.
- W2005163069 cites W2983705614 @default.
- W2005163069 cites W2986577174 @default.
- W2005163069 cites W334178865 @default.
- W2005163069 cites W4234198251 @default.
- W2005163069 cites W4246385507 @default.
- W2005163069 doi "https://doi.org/10.1016/j.ijrobp.2009.04.055" @default.
- W2005163069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19699592" @default.
- W2005163069 hasPublicationYear "2010" @default.
- W2005163069 type Work @default.
- W2005163069 sameAs 2005163069 @default.
- W2005163069 citedByCount "85" @default.
- W2005163069 countsByYear W20051630692012 @default.
- W2005163069 countsByYear W20051630692013 @default.
- W2005163069 countsByYear W20051630692014 @default.
- W2005163069 countsByYear W20051630692015 @default.
- W2005163069 countsByYear W20051630692016 @default.
- W2005163069 countsByYear W20051630692017 @default.
- W2005163069 countsByYear W20051630692018 @default.
- W2005163069 countsByYear W20051630692019 @default.
- W2005163069 countsByYear W20051630692020 @default.