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- W2005163692 abstract "The goal of the study was to evaluate the specificity of serum procalcitonin (PCT) in a large cohort of patients with solid carcinomas at different stages.The study involved 447 patients having histologically confirmed carcinoma of the breast, head and neck, ovary, cervix or non-small cell lung carcinoma. Patients with a history of small cell lung cancer, neuroendocrine tumors, medullary thyroid carcinoma, sepsis, systemic inflammatory syndrome, renal failure and/or serum C-reactive protein above 5 ng/mL were excluded. Additionally, those with suspicious infectious or inflammatory diseases in (18)F-fluorodeoxyglucose positron-emission tomography/computed tomography were also excluded. Serum PCT concentrations were measured using a Kryptor system (BRAHMS) and a clinical cut-off at 0.5 ng/mL was used to define positive results.Serum PCT concentrations did not change at different cancer stages (Kruskal-Wallis, p>0.05). No patient had a PCT concentration >0.5 ng/mL.Our data show that solid carcinomas per se did not increase circulating PCT concentrations, regardless of the histotype and stage of the disease." @default.
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- W2005163692 date "2010-05-04" @default.
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- W2005163692 title "Circulating procalcitonin in aseptic carcinoma patients: a specificity study with <sup>18</sup>F-fluorodeoxyglucose positron-emission tomography/computed tomography as benchmark" @default.
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- W2005163692 doi "https://doi.org/10.1515/cclm.2010.214" @default.
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