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- W2005166404 abstract "G-protein-mediated signaling is the most widely used signaling mechanism in cells and its regulation is crucial for various physiological functions. G-protein-coupled receptor (GPCR) kinases (GRKs) are involved in the desensitization of GPCR signals. Recently, the X-ray crystal structure of GRK2 complexed with Gβγ was demonstrated and revealed the intimate association of three important signaling modules with Gβγ to regulate GRK2 activity." @default.
- W2005166404 created "2016-06-24" @default.
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- W2005166404 date "2004-02-01" @default.
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- W2005166404 title "The structure of the GRK2–Gβγ complex: intimate association of G-protein signaling modules" @default.
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- W2005166404 doi "https://doi.org/10.1016/j.tips.2003.12.006" @default.
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