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- W2005174698 abstract "Hormonal effects on D-xylose penetration in the uncut rat diaphragm were compared with those in the uncut frog peroneus muscle. The in vitro influence of certain hormones on Na+, K+ and glycogen content of frog muscle is described. Parenteral administration of testosterone, desoxycorticosterone, relaxin, and Δ4-cholestenone produced a significant increase in the subsequent in vitro xylose distribution in the rat diaphragm muscle cell. Estradiol and growth hormone were less effective in this regard and thyronine was completely without effect. A frog muscle preparation which retains its properties of contractility as well as Na+ and sugar exclusion for 11 days in vitro is described. The direct action of triiodothyronine, to bring about an increased xylose penetration and a concomitant loss of K+ and glycogen but no change in Na+ distribution, was demonstrated using the frog muscle preparation. These effects of triiodothyronine appear specific since thyronine exhibited no such actions. Cortisol was without direct effect upon xylose distribution, Na+, K+ and glycogen content of frog muscle. DOC exhibited a direct effect on Na+ retention of the frog muscle cell although no influence on K+ or glycogen content was demonstrable. Insulin increased the xylose distribution with similar facility at 3°C and 23°C; thus, the insulin effect on sugar penetration exhibited no temperature dependency in frog muscle. The capability of insulin to augment sugar penetration under conditions wherein no effect on net glycogen could be demonstrated in the presence of glucose is presented. The implications of these results are discussed and certain questions are raised regarding the expression of hormone action." @default.
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- W2005174698 title "Hormones and sugar penetration in skeletal muscle" @default.
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- W2005174698 doi "https://doi.org/10.1016/0010-406x(60)90049-9" @default.
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