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- W2005181879 abstract "The present study was designed to determine whether repeated postnatal blockade of N-methyl-D-aspartate (NMDA) channel produces cognitive deficit in juvenile rats. Rats receive phencyclidine (PCP) intraperitoneally (i.p.) from postnatal Day 5 and continued daily till Day 15. On Day 28, saline- and PCP-treated rats were trained in the Morris water maze task. PCP-treated rats performed as well as the saline-treated rats on the first day of testing, but on the second day of testing they did significantly poorly compared to saline-treated controls. These data suggest that chronic postnatal NMDA channel blockade by PCP impairs processes that enable rats to retain spatial information." @default.
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- W2005181879 date "1998-05-01" @default.
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- W2005181879 title "Repeated Neonatal Phencyclidine Treatment Impairs Performance of a Spatial Task in Juvenile Rats<sup>a</sup>" @default.
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- W2005181879 doi "https://doi.org/10.1111/j.1749-6632.1998.tb08244.x" @default.
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