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- W2005202318 abstract "Significant progress has been made recently in the treatment of patients with severe sepsis. A number of evidencebased therapies improve outcome in these patients. The largest study is the PROWESS study, a randomized placebo controlled trial of activated protein C (APC) vs placebo (Bernard et al, 2001). This reduced mortality by 19% in a highly selected group of patients with severe sepsis. APC has been licensed for use in patients with multiple organ failure secondary to severe sepsis in the UK since October 2002. Practical dilemmas have arisen surrounding its use in certain situations." @default.
- W2005202318 created "2016-06-24" @default.
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- W2005202318 date "2003-11-01" @default.
- W2005202318 modified "2023-09-24" @default.
- W2005202318 title "Should activated protein C be given to a patient who has an epidural?" @default.
- W2005202318 cites W2322121630 @default.
- W2005202318 doi "https://doi.org/10.12968/hosp.2003.64.11.2357" @default.
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