FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005207632> ?p ?o ?g. }

• W2005207632 endingPage "439" @default.
• W2005207632 startingPage "431" @default.
• W2005207632 abstract "Alveolar echinococcosis (AE), caused by the larval stage (metacestode) of the tapeworm Echinococcus multilocularis, exhibits very similar disease characteristics in humans and rodents. Recently, it has been shown that an over-expression of the parasite 14-3-3 protein could be associated to the proliferative growth of the E. multilocularis metacestode. We now demonstrate the expression of this protein at the E. multilocularis oncospheral stage as well. A recombinant E. multilocularis 14-3-3 protein (E14t) was used to vaccinate mice against either primary or secondary experimental E. multilocularis infection in BALB/c mice. Conversely to non-vaccinated but control infected mice, which developed a very weak anti-E14t response during infection, the response elicited in the E14t-vaccinated and subsequently infected animals exhibited a strong reactivity against the parasite 14-3-3 protein. Major differences became apparent between secondarily and primarily infected animals: whereas no protection against secondary infection was achieved by vaccination, vaccinated animals were protected by 97% against challenge primary infection with 2000 E. multilocularis eggs. Consequently, the parasite 14-3-3 molecule appears crucially involved in the early stage of the host–parasite interplay and exhibits potential to be used as target molecule for the development of protective tools against AE." @default.
• W2005207632 created "2016-06-24" @default.
• W2005207632 creator A5006530822 @default.
• W2005207632 creator A5009904850 @default.
• W2005207632 creator A5042834122 @default.
• W2005207632 creator A5081980640 @default.
• W2005207632 date "2003-01-01" @default.
• W2005207632 modified "2023-09-23" @default.
• W2005207632 title "The Echinococcus multilocularis 14-3-3 protein protects mice against primary but not secondary alveolar echinococcosis" @default.
• W2005207632 cites W1502436431 @default.
• W2005207632 cites W1514930961 @default.
• W2005207632 cites W1516385366 @default.
• W2005207632 cites W1518742657 @default.
• W2005207632 cites W1877687377 @default.
• W2005207632 cites W1960257587 @default.
• W2005207632 cites W1965303089 @default.
• W2005207632 cites W1973494319 @default.
• W2005207632 cites W1987084629 @default.
• W2005207632 cites W1988072445 @default.
• W2005207632 cites W1991796203 @default.
• W2005207632 cites W1998147157 @default.
• W2005207632 cites W2001297806 @default.
• W2005207632 cites W2005503643 @default.
• W2005207632 cites W2025643606 @default.
• W2005207632 cites W2033412350 @default.
• W2005207632 cites W2042767415 @default.
• W2005207632 cites W2048913803 @default.
• W2005207632 cites W2054930427 @default.
• W2005207632 cites W2056248153 @default.
• W2005207632 cites W2068943928 @default.
• W2005207632 cites W2072119675 @default.
• W2005207632 cites W2073116921 @default.
• W2005207632 cites W2074569229 @default.
• W2005207632 cites W2094390082 @default.
• W2005207632 cites W2105342913 @default.
• W2005207632 cites W2158412415 @default.
• W2005207632 cites W2161488791 @default.
• W2005207632 doi "https://doi.org/10.1016/s0264-410x(02)00517-0" @default.
• W2005207632 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12531641" @default.
• W2005207632 hasPublicationYear "2003" @default.
• W2005207632 type Work @default.
• W2005207632 sameAs 2005207632 @default.
• W2005207632 citedByCount "61" @default.
• W2005207632 countsByYear W20052076322012 @default.
• W2005207632 countsByYear W20052076322013 @default.
• W2005207632 countsByYear W20052076322015 @default.
• W2005207632 countsByYear W20052076322016 @default.
• W2005207632 countsByYear W20052076322017 @default.
• W2005207632 countsByYear W20052076322018 @default.
• W2005207632 countsByYear W20052076322019 @default.
• W2005207632 countsByYear W20052076322020 @default.
• W2005207632 countsByYear W20052076322021 @default.
• W2005207632 countsByYear W20052076322022 @default.
• W2005207632 countsByYear W20052076322023 @default.
• W2005207632 crossrefType "journal-article" @default.
• W2005207632 hasAuthorship W2005207632A5006530822 @default.
• W2005207632 hasAuthorship W2005207632A5009904850 @default.
• W2005207632 hasAuthorship W2005207632A5042834122 @default.
• W2005207632 hasAuthorship W2005207632A5081980640 @default.
• W2005207632 hasConcept C136764020 @default.
• W2005207632 hasConcept C159047783 @default.
• W2005207632 hasConcept C165901193 @default.
• W2005207632 hasConcept C203014093 @default.
• W2005207632 hasConcept C22070199 @default.
• W2005207632 hasConcept C2779452502 @default.
• W2005207632 hasConcept C2779482186 @default.
• W2005207632 hasConcept C2779687537 @default.
• W2005207632 hasConcept C2779726973 @default.
• W2005207632 hasConcept C2779752401 @default.
• W2005207632 hasConcept C2780340127 @default.
• W2005207632 hasConcept C2910014464 @default.
• W2005207632 hasConcept C41008148 @default.
• W2005207632 hasConcept C71928629 @default.
• W2005207632 hasConcept C86803240 @default.
• W2005207632 hasConcept C90856448 @default.
• W2005207632 hasConceptScore W2005207632C136764020 @default.
• W2005207632 hasConceptScore W2005207632C159047783 @default.
• W2005207632 hasConceptScore W2005207632C165901193 @default.
• W2005207632 hasConceptScore W2005207632C203014093 @default.
• W2005207632 hasConceptScore W2005207632C22070199 @default.
• W2005207632 hasConceptScore W2005207632C2779452502 @default.
• W2005207632 hasConceptScore W2005207632C2779482186 @default.
• W2005207632 hasConceptScore W2005207632C2779687537 @default.
• W2005207632 hasConceptScore W2005207632C2779726973 @default.
• W2005207632 hasConceptScore W2005207632C2779752401 @default.
• W2005207632 hasConceptScore W2005207632C2780340127 @default.
• W2005207632 hasConceptScore W2005207632C2910014464 @default.
• W2005207632 hasConceptScore W2005207632C41008148 @default.
• W2005207632 hasConceptScore W2005207632C71928629 @default.
• W2005207632 hasConceptScore W2005207632C86803240 @default.
• W2005207632 hasConceptScore W2005207632C90856448 @default.
• W2005207632 hasIssue "5-6" @default.
• W2005207632 hasLocation W20052076321 @default.
• W2005207632 hasLocation W20052076322 @default.
• W2005207632 hasOpenAccess W2005207632 @default.
• W2005207632 hasPrimaryLocation W20052076321 @default.
• W2005207632 hasRelatedWork W2005207632 @default.
• W2005207632 hasRelatedWork W2022749749 @default.

• next