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• W2005208522 abstract "A number of epidemiological/observational studies, as well as large-scale randomized intervention studies, have been conducted to provide evidence for the efficacy of ω-3 fatty acids against atherosclerotic diseases. Currently, ω-3 fatty acids are commercially available in many parts of the world containing the same active ingredients as Lotriga(®) (ω-3-acid ethyl esters 90 [O3AE highly concentrated ω-3 fatty acid ethyl esters, consisting of eicosapentaenoic acid-ethyl ester and docosahexaenoic acid-ethyl ester [EPA-E/DHA-E]). A recent head-to-head comparative study of O3AEE90 versus EPA-E demonstrated that O3AEE90 4g/day led to a significantly greater reduction in triglycerides (TG) than EPA-E 1.8g/day and that O3AEE90 2g/day produced comparable effects on TG to those with EPA-E 1.8g/day. While both agents were shown to be useful in lowering TG, the hallmark feature of O3AEE90, that is, the presence of the DHA-E component versus its absence in EPA-E, needs to be further examined for its clinical implications." @default.
• W2005208522 created "2016-06-24" @default.
• W2005208522 creator A5007519585 @default.
• W2005208522 date "2014-10-16" @default.
• W2005208522 modified "2023-09-23" @default.
• W2005208522 title "Omega-3 polyunsaturated fatty acids and cardiovascular disease: an emphasis on omega-3-acid ethyl esters 90 for the treatment of hypertriglyceridemia" @default.
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• W2005208522 doi "https://doi.org/10.1586/14779072.2014.971756" @default.
• W2005208522 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25319059" @default.
• W2005208522 hasPublicationYear "2014" @default.
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