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- W2005236106 abstract "Infection with Staphylococcus aureus is common in all forms of eczema. Production of superantigens by S. ­aureus increases skin inflammation in eczema; antibacterial treatment is thus pivotal. Poor patient compliance is a major cause of treatment failure; combination preparations that contain an antibacterial and a topical steroid and that work quickly can improve compliance and thus treatment outcome. Fusidic acid has advantages over other avail­able topical antibacterial agents – neomycin, gentamicin, clioquinol, chlortetracycline, and the antifungal agent miconazole. The clinical efficacy, antibacterial activity and cosmetic acceptability of fusidic acid/corticosteroid combinations are similar to or better than those of comparator combinations. Fusidic acid/steroid combinations work quickly with observable improvement within the first week. Studies have shown that short-term (2 weeks) use of fusidic acid/corticosteroid combinations does not increase the development of resistance. A new formulation of fusidic acid with betamethasone valerate in a lipid cream also addresses xerosis in eczema." @default.
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- W2005236106 date "2008-01-01" @default.
- W2005236106 modified "2023-09-25" @default.
- W2005236106 title "Chapter 4. Antibacterial/steroid combination therapy in infected eczema" @default.
- W2005236106 doi "https://doi.org/10.2340/00015555-0389" @default.
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