FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005256952> ?p ?o ?g. }

• W2005256952 endingPage "2021" @default.
• W2005256952 startingPage "2016" @default.
• W2005256952 abstract "MCGUIGAN, M. R. M., R. BRONKS, R. U. NEWTON, M. J. SHARMAN, J. C. GRAHAM, D. V. CODY, and W. J. KRAEMER. Muscle fiber characteristics in patients with peripheral arterial disease. Med. Sci. Sports Exerc., Vol. 33, No. 12, 2001, pp. 2016–2021. Purpose There have been conflicting reports of muscle fiber type changes in patients with peripheral arterial disease (PAD). The purpose of this study was to examine the myosin heavy chain (MHC) expression as well as histochemical changes in the gastrocnemius muscle in patients with symptomatic PAD. Methods Needle biopsy specimens were obtained from the medial gastrocnemius of 14 subjects with PAD (mean age (± SD), 69.7 ± 4.8 yr) and eight activity-matched control subjects (mean age, 65.1 ± 6.6 yr). Ankle-brachial index was assessed using Doppler ultrasound to determine the hemodynamic status of the patients, and maximal walking performance was determined during a graded treadmill test. Expression of MHC isoforms was determined by SDS-PAGE. Results The proportion of MHC I was significantly smaller in PAD than in the controls (45.6 ± 9.1% vs 58.8 ± 15.0%). The proportion of MHC IIx was also larger in the subjects with PAD compared with the controls (22.9 ± 9.1% vs 16.0 ± 11.3%). In addition, there was a significant decrease in the cross-sectional area of the type I and type IIA fibers in the subjects with PAD as well as enhanced capillary density. Conclusion This study showed a significant modification in the expression of MHC isoforms and muscle fiber type in the gastrocnemius in patients with symptomatic PAD. These results suggest that muscle ischemia resulting from PAD is an important factor in causing the adaptations in the contractile apparatus of the muscle." @default.
• W2005256952 created "2016-06-24" @default.
• W2005256952 creator A5025501570 @default.
• W2005256952 creator A5027102310 @default.
• W2005256952 creator A5029107268 @default.
• W2005256952 creator A5048206697 @default.
• W2005256952 creator A5071869814 @default.
• W2005256952 creator A5076991700 @default.
• W2005256952 creator A5084702746 @default.
• W2005256952 date "2001-12-01" @default.
• W2005256952 modified "2023-10-15" @default.
• W2005256952 title "Muscle fiber characteristics in patients with peripheral arterial disease" @default.
• W2005256952 cites W1969170437 @default.
• W2005256952 cites W1971815303 @default.
• W2005256952 cites W1996073505 @default.
• W2005256952 cites W2010848569 @default.
• W2005256952 cites W2013284189 @default.
• W2005256952 cites W2018346927 @default.
• W2005256952 cites W2036813167 @default.
• W2005256952 cites W2042284908 @default.
• W2005256952 cites W2050474359 @default.
• W2005256952 cites W2051337042 @default.
• W2005256952 cites W2062305211 @default.
• W2005256952 cites W2069727496 @default.
• W2005256952 cites W2076130859 @default.
• W2005256952 cites W2077500520 @default.
• W2005256952 cites W2087408740 @default.
• W2005256952 cites W2089946259 @default.
• W2005256952 cites W2091363348 @default.
• W2005256952 cites W2092687843 @default.
• W2005256952 cites W2116880688 @default.
• W2005256952 cites W2150201345 @default.
• W2005256952 cites W2169557264 @default.
• W2005256952 cites W2171459275 @default.
• W2005256952 cites W2329425391 @default.
• W2005256952 doi "https://doi.org/10.1097/00005768-200112000-00007" @default.
• W2005256952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11740293" @default.
• W2005256952 hasPublicationYear "2001" @default.
• W2005256952 type Work @default.
• W2005256952 sameAs 2005256952 @default.
• W2005256952 citedByCount "97" @default.
• W2005256952 countsByYear W20052569522012 @default.
• W2005256952 countsByYear W20052569522013 @default.
• W2005256952 countsByYear W20052569522014 @default.
• W2005256952 countsByYear W20052569522015 @default.
• W2005256952 countsByYear W20052569522016 @default.
• W2005256952 countsByYear W20052569522017 @default.
• W2005256952 countsByYear W20052569522018 @default.
• W2005256952 countsByYear W20052569522019 @default.
• W2005256952 countsByYear W20052569522020 @default.
• W2005256952 countsByYear W20052569522021 @default.
• W2005256952 countsByYear W20052569522022 @default.
• W2005256952 countsByYear W20052569522023 @default.
• W2005256952 crossrefType "journal-article" @default.
• W2005256952 hasAuthorship W2005256952A5025501570 @default.
• W2005256952 hasAuthorship W2005256952A5027102310 @default.
• W2005256952 hasAuthorship W2005256952A5029107268 @default.
• W2005256952 hasAuthorship W2005256952A5048206697 @default.
• W2005256952 hasAuthorship W2005256952A5071869814 @default.
• W2005256952 hasAuthorship W2005256952A5076991700 @default.
• W2005256952 hasAuthorship W2005256952A5084702746 @default.
• W2005256952 hasConcept C126322002 @default.
• W2005256952 hasConcept C134018914 @default.
• W2005256952 hasConcept C141071460 @default.
• W2005256952 hasConcept C164705383 @default.
• W2005256952 hasConcept C178853913 @default.
• W2005256952 hasConcept C185592680 @default.
• W2005256952 hasConcept C2775872116 @default.
• W2005256952 hasConcept C2775934546 @default.
• W2005256952 hasConcept C2777466421 @default.
• W2005256952 hasConcept C2778640784 @default.
• W2005256952 hasConcept C2779959927 @default.
• W2005256952 hasConcept C2779999465 @default.
• W2005256952 hasConcept C3018348675 @default.
• W2005256952 hasConcept C46762472 @default.
• W2005256952 hasConcept C55493867 @default.
• W2005256952 hasConcept C6997183 @default.
• W2005256952 hasConcept C71924100 @default.
• W2005256952 hasConceptScore W2005256952C126322002 @default.
• W2005256952 hasConceptScore W2005256952C134018914 @default.
• W2005256952 hasConceptScore W2005256952C141071460 @default.
• W2005256952 hasConceptScore W2005256952C164705383 @default.
• W2005256952 hasConceptScore W2005256952C178853913 @default.
• W2005256952 hasConceptScore W2005256952C185592680 @default.
• W2005256952 hasConceptScore W2005256952C2775872116 @default.
• W2005256952 hasConceptScore W2005256952C2775934546 @default.
• W2005256952 hasConceptScore W2005256952C2777466421 @default.
• W2005256952 hasConceptScore W2005256952C2778640784 @default.
• W2005256952 hasConceptScore W2005256952C2779959927 @default.
• W2005256952 hasConceptScore W2005256952C2779999465 @default.
• W2005256952 hasConceptScore W2005256952C3018348675 @default.
• W2005256952 hasConceptScore W2005256952C46762472 @default.
• W2005256952 hasConceptScore W2005256952C55493867 @default.
• W2005256952 hasConceptScore W2005256952C6997183 @default.
• W2005256952 hasConceptScore W2005256952C71924100 @default.
• W2005256952 hasIssue "12" @default.
• W2005256952 hasLocation W20052569521 @default.
• W2005256952 hasLocation W20052569522 @default.

• next