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- W2005263600 abstract "La toxicité du carbendazime, un fongicide de synthèse à noyau benzidazole, est étudiée sur l'insémination de la carpe commune et de la truite arc-en-ciel et sur le développement précoce de la carpe commune. La toxicité est plus forte, d'au moins deux ordres de grandeur, sur ces phases du cycle vital que sur l'adulte. La résistance de l'embryon croît à la fin de l'activation de l'oeuf pour une intoxication courte et au moment de la fermenture du “blastopore” pour une intoxication longue. La possibilité est suggérée de classer les agents polluants en reliant leur mode d'action physiologique à la distribution des périodes sensibles à leur action, au cours du développment embryonnaire des poissons. L'oeuf de la carpe paraît êntre un matériel favorable pour l'étude des polluants aquatiques. The toxicity of the systemic antimitotic fungicide carbendazim, a benzimidazol compound, was studied both by trout and common carp insemination, as well as on the early development of the common carp. The toxicity is several grades of magnitude higher for these stages of the vital cycle compared with the effect on the adult stages: whereas The Pesticide Manual states that for the adult Carp, an LC100 (24 h) > 1000 mg 1−1 we find, during insemination at pH 9: LC100 (30 min) < 5 mg l−1 and during insemination at pH 7: LC100 (30 min) <2.5 min l−1. During early development we find, for instance, LC100 (30 min) < 5 mg 1−1 before the end of activation and LC100 (24 h) < 1 mg l−1 before the end of epiboly. In the course of insemination, the egg is more sensitive to carbendazim at pH 7 than at pH 9: this difference may be attributed to a greater solubility of the non ionic form of the molecule in the biological membranes. The resistance of the embryo to short treatment grows at the end of activation. This may be attributed to the decrease of the shell permeability during activation. Before the end of activation, the resistance to short intoxication seems to be able to fluctuate, which perhaps corresponds to the existence of sensitive stages in the mitotic cycle. The resistance to an over 24-h exposure increases abruptly at the end of epiboly, which could correspond to a protective part played by the enveloping layer. We suggest the possibility of classifying aquatic pollutants by correlating their physiological mode of action to the resistance profile of the fish embryo. The carp egg seems to be a favourable biological model for studying the effects of aquatic pollutants." @default.
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- W2005263600 title "Influence sur la survie jusqu'a eclosion des embryons de carpe commune (cyprinus carpio l.) apres traitement, pendant la fecondation et le developpement precoce, par le carbendazime, un fongicide antimitotique de synthese" @default.
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- W2005263600 doi "https://doi.org/10.1016/0043-1354(83)90262-2" @default.
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