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- W2005265510 abstract "Free radical scavenging activity of the methanolic extract of the roots of Centaurea centaurium L. (Asteraceae) and its phenolic, non-polar and water fractions was measured using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The phenolic fraction showed high radical-scavenging activity with DPPH (IC50 of 57 µg mL−1) and potent antioxidant properties both on lipid peroxidation and β-carotene bleaching (IC50 of 195 and 5 µg mL−1, respectively). The n-hexane fraction of the extract showed the highest inhibitory activity against α-amylase with an IC50 of 158 µg mL−1. In this fraction, the most abundant constituents were the fatty acids: 11,14-eicosadienoic acid methyl ester, 9-octadecenoic acid methyl ester and 9-octadecenoic acid. Various terpenes, e.g. cypirene, α-zingiberene, β-farnesene, β-santalene, β-bisabolene, β-himachalene and azulene were also present. The LC50 against the brine shrimp nauplii for the methanolic extract was found to be 44.05 µg mL−1, whilst LC50 values for the polyphenolic, lipophilic and water fractions were found to be 157.44, 25.98 and 152.81 µg mL−1, respectively." @default.
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- W2005265510 date "2008-11-10" @default.
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- W2005265510 title "Antioxidant, α-amylase inhibitory and brine-shrimp toxicity studies on<i>Centaurea centaurium</i>L. methanolic root extract" @default.
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- W2005265510 doi "https://doi.org/10.1080/14786410802098071" @default.
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