FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005280256> ?p ?o ?g. }

• W2005280256 endingPage "201" @default.
• W2005280256 startingPage "190" @default.
• W2005280256 abstract "The innervation-induced down-regulation of fetal-type acetylcholine receptor (AChR) expression in developing muscle fibers has largely been attributed to nerve-evoked muscle activity; however, there is increasing evidence that a neural trophic factor also contributes to this receptor down-regulation. Previous studies from this laboratory have shown that neural extracts contain a factor which decreases fetal-type AChR expression in skeletal muscle cell lines and therefore may account for the proposed inhibitory neurotrophic influence. The current study investigated possible intracellular signaling molecules involved in this receptor down-regulation and demonstrated that activation of protein kinase C and p70S6k appeared to be important in receptor down-regulation. Decreases in AChR density were independent of myogenin. In addition, the receptor down-regulation was independent of neuregulin, which also induces p70S6k activity. These studies demonstrate that neural extracts contain an inhibitory factor which can down-regulate fetal-type AChR expression independently of nerve-evoked muscle activity through intracellular signaling molecules which are known to regulate AChR expression. © 2000 John Wiley & Sons, Inc. J Neurobiol 42: 190–201, 2000" @default.
• W2005280256 created "2016-06-24" @default.
• W2005280256 creator A5009444223 @default.
• W2005280256 creator A5068019067 @default.
• W2005280256 creator A5078083767 @default.
• W2005280256 date "2000-02-05" @default.
• W2005280256 modified "2023-10-14" @default.
• W2005280256 title "Intracellular signaling molecules involved in an inhibitory factor-induced decrease in fetal-type AChR expression" @default.
• W2005280256 cites W1733049857 @default.
• W2005280256 cites W1755902553 @default.
• W2005280256 cites W1899771940 @default.
• W2005280256 cites W1941310785 @default.
• W2005280256 cites W1968391774 @default.
• W2005280256 cites W1969442037 @default.
• W2005280256 cites W1973188134 @default.
• W2005280256 cites W1983615672 @default.
• W2005280256 cites W1990654868 @default.
• W2005280256 cites W1990907625 @default.
• W2005280256 cites W1997914540 @default.
• W2005280256 cites W2000614632 @default.
• W2005280256 cites W2007562799 @default.
• W2005280256 cites W2008411984 @default.
• W2005280256 cites W2013830080 @default.
• W2005280256 cites W2015174638 @default.
• W2005280256 cites W2016929237 @default.
• W2005280256 cites W2018274938 @default.
• W2005280256 cites W2019132803 @default.
• W2005280256 cites W2037972708 @default.
• W2005280256 cites W2039427822 @default.
• W2005280256 cites W2039880680 @default.
• W2005280256 cites W2043471865 @default.
• W2005280256 cites W2045751356 @default.
• W2005280256 cites W2046801181 @default.
• W2005280256 cites W2055675775 @default.
• W2005280256 cites W2059781921 @default.
• W2005280256 cites W2065267195 @default.
• W2005280256 cites W2070778596 @default.
• W2005280256 cites W2078256900 @default.
• W2005280256 cites W2081043252 @default.
• W2005280256 cites W2091156745 @default.
• W2005280256 cites W2091723337 @default.
• W2005280256 cites W2097172944 @default.
• W2005280256 cites W2104019822 @default.
• W2005280256 cites W2121848789 @default.
• W2005280256 cites W2136674751 @default.
• W2005280256 cites W2151127067 @default.
• W2005280256 cites W2163548105 @default.
• W2005280256 cites W2167366126 @default.
• W2005280256 doi "https://doi.org/10.1002/(sici)1097-4695(20000205)42:2<190::aid-neu3>3.0.co;2-j" @default.
• W2005280256 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10640326" @default.
• W2005280256 hasPublicationYear "2000" @default.
• W2005280256 type Work @default.
• W2005280256 sameAs 2005280256 @default.
• W2005280256 citedByCount "2" @default.
• W2005280256 crossrefType "journal-article" @default.
• W2005280256 hasAuthorship W2005280256A5009444223 @default.
• W2005280256 hasAuthorship W2005280256A5068019067 @default.
• W2005280256 hasAuthorship W2005280256A5078083767 @default.
• W2005280256 hasConcept C126322002 @default.
• W2005280256 hasConcept C134018914 @default.
• W2005280256 hasConcept C160539049 @default.
• W2005280256 hasConcept C170493617 @default.
• W2005280256 hasConcept C17077164 @default.
• W2005280256 hasConcept C185323287 @default.
• W2005280256 hasConcept C2778560701 @default.
• W2005280256 hasConcept C2779959927 @default.
• W2005280256 hasConcept C3763915 @default.
• W2005280256 hasConcept C55493867 @default.
• W2005280256 hasConcept C62478195 @default.
• W2005280256 hasConcept C71924100 @default.
• W2005280256 hasConcept C79879829 @default.
• W2005280256 hasConcept C80161118 @default.
• W2005280256 hasConcept C86803240 @default.
• W2005280256 hasConcept C92020748 @default.
• W2005280256 hasConcept C95444343 @default.
• W2005280256 hasConcept C97816823 @default.
• W2005280256 hasConceptScore W2005280256C126322002 @default.
• W2005280256 hasConceptScore W2005280256C134018914 @default.
• W2005280256 hasConceptScore W2005280256C160539049 @default.
• W2005280256 hasConceptScore W2005280256C170493617 @default.
• W2005280256 hasConceptScore W2005280256C17077164 @default.
• W2005280256 hasConceptScore W2005280256C185323287 @default.
• W2005280256 hasConceptScore W2005280256C2778560701 @default.
• W2005280256 hasConceptScore W2005280256C2779959927 @default.
• W2005280256 hasConceptScore W2005280256C3763915 @default.
• W2005280256 hasConceptScore W2005280256C55493867 @default.
• W2005280256 hasConceptScore W2005280256C62478195 @default.
• W2005280256 hasConceptScore W2005280256C71924100 @default.
• W2005280256 hasConceptScore W2005280256C79879829 @default.
• W2005280256 hasConceptScore W2005280256C80161118 @default.
• W2005280256 hasConceptScore W2005280256C86803240 @default.
• W2005280256 hasConceptScore W2005280256C92020748 @default.
• W2005280256 hasConceptScore W2005280256C95444343 @default.
• W2005280256 hasConceptScore W2005280256C97816823 @default.
• W2005280256 hasIssue "2" @default.
• W2005280256 hasLocation W20052802561 @default.
• W2005280256 hasLocation W20052802562 @default.
• W2005280256 hasOpenAccess W2005280256 @default.

• next