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- W2005280280 endingPage "30" @default.
- W2005280280 startingPage "18" @default.
- W2005280280 abstract "To provide a review on current knowledge about the pathogenesis, epidemiology, and clinical complications of persistent hyperparathyroidism after kidney transplantation (3HPT) and to discuss the surgical approaches.3HPT usually regresses within the first months after transplantation. Parathyroidectomy for 3HPT is therefore not usually needed. Consequently, few studies have been published regarding the best medical management for 3HPT and indications for parathyroidectomy.Medical literature databases were searched for studies on the surgical treatment of 3HPT published in English.Forty-one studies were identified and included in this review.3HPT most commonly occurs in patients who have severe secondary hyperparathyroidism at the time of transplantation. Indications for parathyroidectomy in patients with 3HPT include persistent severe hypercalcemia, defined as a serum calcium level greater than 11.5 mg/dl, unexplained renal function deterioration, or progressive bone mineral density loss. Published studies suggest that the best surgical approach for patients with 3HPT is subtotal parathyroidectomy or total parathyroidectomy with autotransplantation. 3HPT poses important health risks, particularly concerning bone density and the cardiovascular system. Because spontaneous improvement of parathyroid function is uncommon after 3 months of transplantation, waiting for more than 6 months before parathyroidectomy should be discouraged." @default.
- W2005280280 created "2016-06-24" @default.
- W2005280280 creator A5004339384 @default.
- W2005280280 creator A5068545184 @default.
- W2005280280 creator A5083782401 @default.
- W2005280280 creator A5089773064 @default.
- W2005280280 date "2008-07-01" @default.
- W2005280280 modified "2023-10-15" @default.
- W2005280280 title "Surgical Treatment of Persistent Hyperparathyroidism After Renal Transplantation" @default.
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