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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005283533> ?p ?o ?g. }

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• W2005283533 abstract "Ten human neural tumor lines and three established from normal human brain were analyzed for sensitivities to natural killer (NK) cytolysis. Compared to MOLT-4, fetal brain cells were sensitive, but those from adult brain and eight of ten neural tumor cell lines demonstrated marked NK resistance. The frequencies of target-binding cells (TBC) and single-cell lysis of glioma cells bound within tumor cell conjugates demonstrated that the resistance of two lines was explained either by a decrease in the frequencies of TBC or reduced ability of bound NK cells to lyse the tumor cell conjugates. A third resistant line demonstrated decreases in both TBC and tumor cell conjugate lysis. Two glioma lines with less NK resistance had greater frequencies of TBC or conjugate lysis than the resistant lines. Thus, NK resistance can result from decreased recognition of targets, diminished NK lysis of bound targets, or a combination of both." @default.
• W2005283533 created "2016-06-24" @default.
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• W2005283533 date "1985-02-01" @default.
• W2005283533 modified "2023-09-25" @default.
• W2005283533 title "Natural killer activity against cultured human neural tumor and fetal brain cells" @default.
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• W2005283533 doi "https://doi.org/10.1016/0008-8749(85)90213-8" @default.
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