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- W2005298143 abstract "Acute rheumatic fever (ARF), is a systemic inflammatory disease etiologically related to infection with group A beta hemolytic streptococcus, characterized by a broad spectrum of disorders in cellular immunity. To estimate the activity of the immunopathological process in patients with ARF, plasma nitric oxide metabolities (NOx) concentrations, IL-1alpha and IL-2 levels were investigated in 22 patients with ARF at the time on admission, and after 3 months, in children with chronic rheumatic heart disease (CRHD). Plasma NOx concentrations, IL-1alpha and IL/2 levels in patients with ARF on admission were significantly higher than in the same patients 3 months later, and higher than in CRHD, or controls. Increased plasma NO may be a useful index for the quantitative assessment of the activity during immunological challenge. This information may be useful for the prognosis and monitoring of ARF." @default.
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- W2005298143 date "2003-01-01" @default.
- W2005298143 modified "2023-10-06" @default.
- W2005298143 title "Nitric Oxide Metabolities in Acute Rheumatic Fever" @default.
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- W2005298143 doi "https://doi.org/10.1620/tjem.199.135" @default.
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