Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005349078> ?p ?o ?g. }
- W2005349078 endingPage "9" @default.
- W2005349078 startingPage "1" @default.
- W2005349078 abstract "Mesenchymal stem cells (MSCs) are of special interest as therapeutic agents in the settings of both chronic inflammatory and autoimmune diseases. Toll-like receptors (TLR) ligands have been linked with the perpetuation of inflammation in a number of chronic inflammatory diseases due to the permanent exposure of the immune system to TLR-specific stimuli. Therefore, MSCs employed in therapy can be potentially exposed to TLR ligands, which may modulate MSC therapeutic potential in vivo. Recent results demonstrate that MSCs are activated by TLR ligands leading to modulation of the differentiation, migration, proliferation, survival, and immunosuppression capacities. However inconsistent results among authors have been reported suggesting that the source of MSCs, TLR stimuli employed or culture conditions play a role. Notably, activation by TLR ligands has not been reported to modulate the “immunoprivileged” phenotype of MSCs which is of special relevance regarding the use of allogeneic MSC-based therapies. In this review, we discuss the available data on the modulation of MSCs activity through TLR signalling." @default.
- W2005349078 created "2016-06-24" @default.
- W2005349078 creator A5022981123 @default.
- W2005349078 creator A5029682067 @default.
- W2005349078 date "2010-01-01" @default.
- W2005349078 modified "2023-09-30" @default.
- W2005349078 title "Modulation of Adult Mesenchymal Stem Cells Activity by Toll-Like Receptors: Implications on Therapeutic Potential" @default.
- W2005349078 cites W1488196937 @default.
- W2005349078 cites W1489842152 @default.
- W2005349078 cites W1515599953 @default.
- W2005349078 cites W1591714343 @default.
- W2005349078 cites W1718946616 @default.
- W2005349078 cites W1965425745 @default.
- W2005349078 cites W1968255500 @default.
- W2005349078 cites W1973326127 @default.
- W2005349078 cites W1975517608 @default.
- W2005349078 cites W1976371737 @default.
- W2005349078 cites W1982408656 @default.
- W2005349078 cites W1991731944 @default.
- W2005349078 cites W1995744610 @default.
- W2005349078 cites W1997797226 @default.
- W2005349078 cites W2009626854 @default.
- W2005349078 cites W2011653132 @default.
- W2005349078 cites W2012968942 @default.
- W2005349078 cites W2013123708 @default.
- W2005349078 cites W2016862474 @default.
- W2005349078 cites W2018475901 @default.
- W2005349078 cites W2025294489 @default.
- W2005349078 cites W2025371271 @default.
- W2005349078 cites W2034021377 @default.
- W2005349078 cites W2035976926 @default.
- W2005349078 cites W2041243709 @default.
- W2005349078 cites W2044695442 @default.
- W2005349078 cites W2044875340 @default.
- W2005349078 cites W2045895870 @default.
- W2005349078 cites W2047003816 @default.
- W2005349078 cites W2051297632 @default.
- W2005349078 cites W2053455572 @default.
- W2005349078 cites W2054134729 @default.
- W2005349078 cites W2054274983 @default.
- W2005349078 cites W2055569470 @default.
- W2005349078 cites W2056725513 @default.
- W2005349078 cites W2068043688 @default.
- W2005349078 cites W2071756012 @default.
- W2005349078 cites W2078171389 @default.
- W2005349078 cites W2086304264 @default.
- W2005349078 cites W2087353148 @default.
- W2005349078 cites W2088500471 @default.
- W2005349078 cites W2090886213 @default.
- W2005349078 cites W2095666785 @default.
- W2005349078 cites W2097599737 @default.
- W2005349078 cites W2099246870 @default.
- W2005349078 cites W2106117542 @default.
- W2005349078 cites W2107503723 @default.
- W2005349078 cites W2111727066 @default.
- W2005349078 cites W2115185894 @default.
- W2005349078 cites W2115788075 @default.
- W2005349078 cites W2124579461 @default.
- W2005349078 cites W2126659405 @default.
- W2005349078 cites W2126734687 @default.
- W2005349078 cites W2129682008 @default.
- W2005349078 cites W2129708174 @default.
- W2005349078 cites W2131004666 @default.
- W2005349078 cites W2133426555 @default.
- W2005349078 cites W2136078305 @default.
- W2005349078 cites W2140413558 @default.
- W2005349078 cites W2144337206 @default.
- W2005349078 cites W2149913704 @default.
- W2005349078 cites W2158048826 @default.
- W2005349078 cites W2159999899 @default.
- W2005349078 cites W2161497340 @default.
- W2005349078 cites W2161846095 @default.
- W2005349078 cites W2169367453 @default.
- W2005349078 cites W2171373028 @default.
- W2005349078 cites W2214992795 @default.
- W2005349078 cites W4230951035 @default.
- W2005349078 cites W4249383371 @default.
- W2005349078 doi "https://doi.org/10.1155/2010/865601" @default.
- W2005349078 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2902124" @default.
- W2005349078 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20628526" @default.
- W2005349078 hasPublicationYear "2010" @default.
- W2005349078 type Work @default.
- W2005349078 sameAs 2005349078 @default.
- W2005349078 citedByCount "152" @default.
- W2005349078 countsByYear W20053490782012 @default.
- W2005349078 countsByYear W20053490782013 @default.
- W2005349078 countsByYear W20053490782014 @default.
- W2005349078 countsByYear W20053490782015 @default.
- W2005349078 countsByYear W20053490782016 @default.
- W2005349078 countsByYear W20053490782017 @default.
- W2005349078 countsByYear W20053490782018 @default.
- W2005349078 countsByYear W20053490782019 @default.
- W2005349078 countsByYear W20053490782020 @default.
- W2005349078 countsByYear W20053490782021 @default.
- W2005349078 countsByYear W20053490782022 @default.
- W2005349078 countsByYear W20053490782023 @default.
- W2005349078 crossrefType "journal-article" @default.
- W2005349078 hasAuthorship W2005349078A5022981123 @default.