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- W2005356917 abstract "The structure of a gene coding for bombinin-like peptides (BLP) in Bombina orientalis was determined. It comprises two exons separated by a 1337 bp intron. Exon 1 codes for the signal peptide, while exon 2 contains the genetic information for BLP-7 and a bombinin H-type peptide (GH-2). The promoter region contains putative recognition sites for nuclear factors, such as NF-IL6 and NF-kappaB. The analysis of the structure of this gene, compared with that of the previously reported BLP-3 gene sequence, suggests the occurrence of a gene duplication event, rather than an alternative splicing mechanism, which leads to the generation of both inter- and intra-families variability in this class of cytolytic peptides. Furthermore, chromosome walking analysis indicates that this gene family is not densely clustered." @default.
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- W2005356917 date "2000-11-01" @default.
- W2005356917 modified "2023-10-12" @default.
- W2005356917 title "Sequence of a gene from Bombina orientalis coding for the antimicrobial peptide BLP-7" @default.
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- W2005356917 doi "https://doi.org/10.1016/s0196-9781(00)00317-x" @default.
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