FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005359834> ?p ?o ?g. }

• W2005359834 endingPage "161" @default.
• W2005359834 startingPage "153" @default.
• W2005359834 abstract "The ovarian steroids estradiol (E(2)) and progesterone (P) act on target neurons in the hypothalamus and preoptic area to coordinate the expression of female reproductive behaviors with the timing of the preovulatory luteinizing hormone (LH) surge. This chapter will summarize evidence that E(2) and P facilitation of the receptive component of female reproductive behavior, lordosis, involves changes in both the expression of and intracellular signal transduction pathways engaged by alpha(1)-adrenergic receptors in the hypothalamus and preoptic area. The alpha(1)-adrenoceptors are thought to mediate the facilitatory effects of the catecholamine neurotransmitter norepinephrine on both lordosis behavior and LH release. E(2) first induces the expression of the alpha(1B)-adrenergic receptor subtype in the hypothalamus and preoptic area. P then acts in an E(2)-dependent manner to promote linkage of hypothalamic alpha(1)-adrenoceptors to an intracellular signaling pathway involving nitric oxide and cyclic GMP. This chapter will also describe recent findings that implicate brain insulin-like growth factor-I (IGF-I) receptors as obligatory co-mediators of hormonal regulation of hypothalamic alpha(1)-adrenoceptors and female neuroendocrine function. Additional studies suggest that E(2) and IGF-I facilitate lordosis behavior by activating kinases traditionally associated with growth factor signal transduction (mitogen-activated protein kinases and phosphatidlyinositol-3-kinases). These molecular events are proposed to help coordinate the timing of ovulation with the expression of sexual receptivity, thereby maximizing reproductive success." @default.
• W2005359834 created "2016-06-24" @default.
• W2005359834 creator A5035809946 @default.
• W2005359834 date "2003-12-01" @default.
• W2005359834 modified "2023-09-23" @default.
• W2005359834 title "Ovarian Steroid and Growth Factor Regulation of Female Reproductive Function Involves Modification of Hypothalamic α₁-Adrenoceptor Signaling" @default.
• W2005359834 cites W1518422235 @default.
• W2005359834 cites W1537934849 @default.
• W2005359834 cites W1564409279 @default.
• W2005359834 cites W1584419477 @default.
• W2005359834 cites W1673944246 @default.
• W2005359834 cites W1836032268 @default.
• W2005359834 cites W1929864068 @default.
• W2005359834 cites W1969715795 @default.
• W2005359834 cites W1970285990 @default.
• W2005359834 cites W1977526231 @default.
• W2005359834 cites W1978720902 @default.
• W2005359834 cites W1993167968 @default.
• W2005359834 cites W1994526084 @default.
• W2005359834 cites W1996892647 @default.
• W2005359834 cites W2010026151 @default.
• W2005359834 cites W2010369216 @default.
• W2005359834 cites W2013687317 @default.
• W2005359834 cites W2017111453 @default.
• W2005359834 cites W2017185235 @default.
• W2005359834 cites W2017236621 @default.
• W2005359834 cites W2019291914 @default.
• W2005359834 cites W2021451131 @default.
• W2005359834 cites W2026307678 @default.
• W2005359834 cites W2026369110 @default.
• W2005359834 cites W2030884639 @default.
• W2005359834 cites W2031062785 @default.
• W2005359834 cites W2036957553 @default.
• W2005359834 cites W2038791497 @default.
• W2005359834 cites W2039677804 @default.
• W2005359834 cites W2041683554 @default.
• W2005359834 cites W2055071758 @default.
• W2005359834 cites W2073576669 @default.
• W2005359834 cites W2073689314 @default.
• W2005359834 cites W2075564085 @default.
• W2005359834 cites W2079393032 @default.
• W2005359834 cites W2080867526 @default.
• W2005359834 cites W2081797127 @default.
• W2005359834 cites W2086173581 @default.
• W2005359834 cites W2089415674 @default.
• W2005359834 cites W2093896329 @default.
• W2005359834 cites W2102041216 @default.
• W2005359834 cites W2104062900 @default.
• W2005359834 cites W2126000686 @default.
• W2005359834 cites W2127604481 @default.
• W2005359834 cites W2134674714 @default.
• W2005359834 cites W2151204403 @default.
• W2005359834 cites W2315528486 @default.
• W2005359834 cites W3022176029 @default.
• W2005359834 cites W4233625507 @default.
• W2005359834 cites W4233694240 @default.
• W2005359834 cites W977066705 @default.
• W2005359834 doi "https://doi.org/10.1196/annals.1286.015" @default.
• W2005359834 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14993049" @default.
• W2005359834 hasPublicationYear "2003" @default.
• W2005359834 type Work @default.
• W2005359834 sameAs 2005359834 @default.
• W2005359834 citedByCount "25" @default.
• W2005359834 countsByYear W20053598342012 @default.
• W2005359834 countsByYear W20053598342015 @default.
• W2005359834 countsByYear W20053598342017 @default.
• W2005359834 countsByYear W20053598342018 @default.
• W2005359834 countsByYear W20053598342019 @default.
• W2005359834 crossrefType "journal-article" @default.
• W2005359834 hasAuthorship W2005359834A5035809946 @default.
• W2005359834 hasConcept C126322002 @default.
• W2005359834 hasConcept C134018914 @default.
• W2005359834 hasConcept C170493617 @default.
• W2005359834 hasConcept C185592680 @default.
• W2005359834 hasConcept C2776451244 @default.
• W2005359834 hasConcept C2777003273 @default.
• W2005359834 hasConcept C2778506572 @default.
• W2005359834 hasConcept C2780626132 @default.
• W2005359834 hasConcept C62478195 @default.
• W2005359834 hasConcept C71315377 @default.
• W2005359834 hasConcept C71924100 @default.
• W2005359834 hasConcept C8264082 @default.
• W2005359834 hasConcept C86803240 @default.
• W2005359834 hasConcept C95444343 @default.
• W2005359834 hasConceptScore W2005359834C126322002 @default.
• W2005359834 hasConceptScore W2005359834C134018914 @default.
• W2005359834 hasConceptScore W2005359834C170493617 @default.
• W2005359834 hasConceptScore W2005359834C185592680 @default.
• W2005359834 hasConceptScore W2005359834C2776451244 @default.
• W2005359834 hasConceptScore W2005359834C2777003273 @default.
• W2005359834 hasConceptScore W2005359834C2778506572 @default.
• W2005359834 hasConceptScore W2005359834C2780626132 @default.
• W2005359834 hasConceptScore W2005359834C62478195 @default.
• W2005359834 hasConceptScore W2005359834C71315377 @default.
• W2005359834 hasConceptScore W2005359834C71924100 @default.
• W2005359834 hasConceptScore W2005359834C8264082 @default.
• W2005359834 hasConceptScore W2005359834C86803240 @default.
• W2005359834 hasConceptScore W2005359834C95444343 @default.

• next