Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005369912> ?p ?o ?g. }
- W2005369912 endingPage "115" @default.
- W2005369912 startingPage "92" @default.
- W2005369912 abstract "Cell therapy is emerging as a viable therapy to restore neurological function after stroke. Many types of stem/progenitor cells from different sources have been explored for their feasibility and efficacy for the treatment of stroke. Transplanted cells not only have the potential to replace the lost circuitry, but also produce growth and trophic factors, or stimulate the release of such factors from host brain cells, thereby enhancing endogenous brain repair processes. Although stem/progenitor cells have shown a promising role in ischemic stroke in experimental studies as well as initial clinical pilot studies, cellular therapy is still at an early stage in humans. Many critical issues need to be addressed including the therapeutic time window, cell type selection, delivery route, and in vivo monitoring of their migration pattern. This review attempts to provide a comprehensive synopsis of preclinical evidence and clinical experience of various donor cell types, their restorative mechanisms, delivery routes, imaging strategies, future prospects and challenges for translating cell therapies as a neurorestorative regimen in clinical applications." @default.
- W2005369912 created "2016-06-24" @default.
- W2005369912 creator A5002792067 @default.
- W2005369912 creator A5005605929 @default.
- W2005369912 creator A5008178802 @default.
- W2005369912 creator A5012660765 @default.
- W2005369912 creator A5020384051 @default.
- W2005369912 creator A5025564811 @default.
- W2005369912 creator A5030218520 @default.
- W2005369912 creator A5046778284 @default.
- W2005369912 creator A5048134021 @default.
- W2005369912 creator A5066886337 @default.
- W2005369912 creator A5072552462 @default.
- W2005369912 date "2014-04-01" @default.
- W2005369912 modified "2023-10-12" @default.
- W2005369912 title "Cell based therapies for ischemic stroke: From basic science to bedside" @default.
- W2005369912 cites W107917948 @default.
- W2005369912 cites W1481623655 @default.
- W2005369912 cites W1487852103 @default.
- W2005369912 cites W1539462532 @default.
- W2005369912 cites W1564060543 @default.
- W2005369912 cites W1575233743 @default.
- W2005369912 cites W1578543970 @default.
- W2005369912 cites W1592390749 @default.
- W2005369912 cites W1662899239 @default.
- W2005369912 cites W1674673636 @default.
- W2005369912 cites W1709981408 @default.
- W2005369912 cites W1761567378 @default.
- W2005369912 cites W1766509663 @default.
- W2005369912 cites W1916760490 @default.
- W2005369912 cites W1965404154 @default.
- W2005369912 cites W1965579454 @default.
- W2005369912 cites W1966339894 @default.
- W2005369912 cites W1966484579 @default.
- W2005369912 cites W1966545752 @default.
- W2005369912 cites W1967239173 @default.
- W2005369912 cites W1967592473 @default.
- W2005369912 cites W1967764688 @default.
- W2005369912 cites W1967958787 @default.
- W2005369912 cites W1968262266 @default.
- W2005369912 cites W1970007383 @default.
- W2005369912 cites W1970692199 @default.
- W2005369912 cites W1971207083 @default.
- W2005369912 cites W1971212714 @default.
- W2005369912 cites W1971218073 @default.
- W2005369912 cites W1971981920 @default.
- W2005369912 cites W1973392262 @default.
- W2005369912 cites W1973838857 @default.
- W2005369912 cites W1973881356 @default.
- W2005369912 cites W1973890292 @default.
- W2005369912 cites W1974173343 @default.
- W2005369912 cites W1974517039 @default.
- W2005369912 cites W1974547403 @default.
- W2005369912 cites W1976638015 @default.
- W2005369912 cites W1976968085 @default.
- W2005369912 cites W1977450644 @default.
- W2005369912 cites W1978092005 @default.
- W2005369912 cites W1979561481 @default.
- W2005369912 cites W1979692226 @default.
- W2005369912 cites W1980552126 @default.
- W2005369912 cites W1980860710 @default.
- W2005369912 cites W1981019690 @default.
- W2005369912 cites W1981399914 @default.
- W2005369912 cites W1981501194 @default.
- W2005369912 cites W1982132497 @default.
- W2005369912 cites W1982561969 @default.
- W2005369912 cites W1982580798 @default.
- W2005369912 cites W1982738871 @default.
- W2005369912 cites W1982998336 @default.
- W2005369912 cites W1983274440 @default.
- W2005369912 cites W1983586074 @default.
- W2005369912 cites W1985226366 @default.
- W2005369912 cites W1987167495 @default.
- W2005369912 cites W1987270591 @default.
- W2005369912 cites W1987907335 @default.
- W2005369912 cites W1987907711 @default.
- W2005369912 cites W1989560466 @default.
- W2005369912 cites W1989581431 @default.
- W2005369912 cites W1990232805 @default.
- W2005369912 cites W1990281869 @default.
- W2005369912 cites W1991055478 @default.
- W2005369912 cites W1991720187 @default.
- W2005369912 cites W1991721676 @default.
- W2005369912 cites W1991997127 @default.
- W2005369912 cites W1992074285 @default.
- W2005369912 cites W1992533377 @default.
- W2005369912 cites W1993220539 @default.
- W2005369912 cites W1993925802 @default.
- W2005369912 cites W1993965974 @default.
- W2005369912 cites W1995232831 @default.
- W2005369912 cites W1997018751 @default.
- W2005369912 cites W1998156567 @default.
- W2005369912 cites W1998412056 @default.
- W2005369912 cites W1998463679 @default.
- W2005369912 cites W1999181098 @default.
- W2005369912 cites W1999494893 @default.
- W2005369912 cites W2001525797 @default.
- W2005369912 cites W2001672245 @default.