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• W2005370365 abstract "Abstract An efficient and straightforward approach to the synthesis of 6-aryl-3-cyano-5-alkylamino-1-p-tolyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones 8 has been developed from the readily commercially available starting materials 4-methylaniline and malononitrile in five steps. The key to the pyrazolo[4, 3-d]pyrimidin-7(6H)-ones relies on an iminophosphorane-mediated annulation, followed by a nucleophilic addition with amines. The structures of the title compounds are clearly characterized by IR, 1H NMR, MS, elemental analysis or X-ray diffraction crystallography." @default.
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• W2005370365 date "2010-07-01" @default.
• W2005370365 modified "2023-09-25" @default.
• W2005370365 title "Regiospecific synthesis of 6-aryl-3-cyano-5-alkylamino/arylamino-1-p-tolyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones via iminophosphorane-mediated annulation" @default.
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• W2005370365 doi "https://doi.org/10.1016/j.tet.2010.04.114" @default.
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