FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005372271> ?p ?o ?g. }

• W2005372271 endingPage "270" @default.
• W2005372271 startingPage "263" @default.
• W2005372271 abstract "An association of primary biliary cirrhosis (PBC) with human leukocyte antigen (HLA) class II has been reported in previous studies based on the results of serological HLA typing. To evaluate the association between PBC and HLA class II more precisely, we performed HLA-DRB1 and DPB1 genotyping in 53 Japanese patients with PBC using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. In DRB1 genotyping, the frequency of the*0803 allele was significantly higher in patients with PBC than that in control subjects. Twenty out of 53 patients were*0803 positive (37.7%), whereas only five out of 60 controls (8.3%) had the allele (relative risk = 6.67;P < 0.001; correctedP < 0.05). In DPB1 genotyping, there was no significant difference in the frequency of the DPB1 alleles between patients with PBC and controls. Amino acid analysis of the DRβ chain revealed that the frequency of leucine at position 74 was significantly higher in patients with PBC than that in controls. These results suggest that HLA-DRB1*0803 allele and a subsequent amino acid substitution encoded by the polymorphic regions of the allele may play an important role in the pathogenesis of PBC." @default.
• W2005372271 created "2016-06-24" @default.
• W2005372271 creator A5003050248 @default.
• W2005372271 creator A5005137443 @default.
• W2005372271 creator A5048746791 @default.
• W2005372271 creator A5069065380 @default.
• W2005372271 creator A5075213835 @default.
• W2005372271 creator A5079429350 @default.
• W2005372271 creator A5083904075 @default.
• W2005372271 date "1994-09-01" @default.
• W2005372271 modified "2023-09-24" @default.
• W2005372271 title "Susceptibility to primary biliary cirrhosis is associated with human leukocyte antigen DRB10803 in Japanese patients" @default.
• W2005372271 cites W1559477571 @default.
• W2005372271 cites W1968942681 @default.
• W2005372271 cites W1977172170 @default.
• W2005372271 cites W1998531275 @default.
• W2005372271 cites W2001412093 @default.
• W2005372271 cites W2006750223 @default.
• W2005372271 cites W2075507466 @default.
• W2005372271 cites W2078028672 @default.
• W2005372271 cites W2084952943 @default.
• W2005372271 cites W2092636293 @default.
• W2005372271 cites W2098783054 @default.
• W2005372271 cites W2149610733 @default.
• W2005372271 cites W2150048405 @default.
• W2005372271 cites W2155233367 @default.
• W2005372271 cites W2157602452 @default.
• W2005372271 cites W2171289901 @default.
• W2005372271 cites W2320869106 @default.
• W2005372271 cites W2463961170 @default.
• W2005372271 doi "https://doi.org/10.1016/0928-4346(94)90061-2" @default.
• W2005372271 hasPublicationYear "1994" @default.
• W2005372271 type Work @default.
• W2005372271 sameAs 2005372271 @default.
• W2005372271 citedByCount "17" @default.
• W2005372271 countsByYear W20053722712012 @default.
• W2005372271 countsByYear W20053722712018 @default.
• W2005372271 crossrefType "journal-article" @default.
• W2005372271 hasAuthorship W2005372271A5003050248 @default.
• W2005372271 hasAuthorship W2005372271A5005137443 @default.
• W2005372271 hasAuthorship W2005372271A5048746791 @default.
• W2005372271 hasAuthorship W2005372271A5069065380 @default.
• W2005372271 hasAuthorship W2005372271A5075213835 @default.
• W2005372271 hasAuthorship W2005372271A5079429350 @default.
• W2005372271 hasAuthorship W2005372271A5083904075 @default.
• W2005372271 hasConcept C104317684 @default.
• W2005372271 hasConcept C135763542 @default.
• W2005372271 hasConcept C147483822 @default.
• W2005372271 hasConcept C159654299 @default.
• W2005372271 hasConcept C180754005 @default.
• W2005372271 hasConcept C188280979 @default.
• W2005372271 hasConcept C203014093 @default.
• W2005372271 hasConcept C2779075594 @default.
• W2005372271 hasConcept C2780366471 @default.
• W2005372271 hasConcept C2780942790 @default.
• W2005372271 hasConcept C2781209916 @default.
• W2005372271 hasConcept C2994419564 @default.
• W2005372271 hasConcept C31467283 @default.
• W2005372271 hasConcept C37463918 @default.
• W2005372271 hasConcept C45189115 @default.
• W2005372271 hasConcept C49105822 @default.
• W2005372271 hasConcept C54355233 @default.
• W2005372271 hasConcept C86803240 @default.
• W2005372271 hasConceptScore W2005372271C104317684 @default.
• W2005372271 hasConceptScore W2005372271C135763542 @default.
• W2005372271 hasConceptScore W2005372271C147483822 @default.
• W2005372271 hasConceptScore W2005372271C159654299 @default.
• W2005372271 hasConceptScore W2005372271C180754005 @default.
• W2005372271 hasConceptScore W2005372271C188280979 @default.
• W2005372271 hasConceptScore W2005372271C203014093 @default.
• W2005372271 hasConceptScore W2005372271C2779075594 @default.
• W2005372271 hasConceptScore W2005372271C2780366471 @default.
• W2005372271 hasConceptScore W2005372271C2780942790 @default.
• W2005372271 hasConceptScore W2005372271C2781209916 @default.
• W2005372271 hasConceptScore W2005372271C2994419564 @default.
• W2005372271 hasConceptScore W2005372271C31467283 @default.
• W2005372271 hasConceptScore W2005372271C37463918 @default.
• W2005372271 hasConceptScore W2005372271C45189115 @default.
• W2005372271 hasConceptScore W2005372271C49105822 @default.
• W2005372271 hasConceptScore W2005372271C54355233 @default.
• W2005372271 hasConceptScore W2005372271C86803240 @default.
• W2005372271 hasIssue "5" @default.
• W2005372271 hasLocation W20053722711 @default.
• W2005372271 hasOpenAccess W2005372271 @default.
• W2005372271 hasPrimaryLocation W20053722711 @default.
• W2005372271 hasRelatedWork W1673949914 @default.
• W2005372271 hasRelatedWork W2037393811 @default.
• W2005372271 hasRelatedWork W2399175424 @default.
• W2005372271 hasRelatedWork W2407585918 @default.
• W2005372271 hasRelatedWork W2410436422 @default.
• W2005372271 hasRelatedWork W2465621080 @default.
• W2005372271 hasRelatedWork W2563618055 @default.
• W2005372271 hasRelatedWork W3159453876 @default.
• W2005372271 hasRelatedWork W3203513527 @default.
• W2005372271 hasRelatedWork W2092187963 @default.
• W2005372271 hasVolume "2" @default.
• W2005372271 isParatext "false" @default.
• W2005372271 isRetracted "false" @default.

• next