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- W2005374674 abstract "The effects of anorexia nervosa on skin thickness, skin collagen content and bone density were investigated in a cross-sectional study of 36 women with anorexia nervosa with a 4-year median duration of amenorrhoea and compared with a group of 33 women of comparable age without anorexia and with normal periods. The median skin thickness, assessed radiologically, was significantly reduced (P<0·01) from 0·88 mm in the comparison group to 0·70 mm in the anorectic group and the median collagen content was significantly reduced from 209 μg/mm2 in the comparison group to 164 μg/mm2 in the anorectic group (P<0·05). The median bone density in the comparison group was 0·93 gHA/cm2 at the lumbar spine and 0·84 gHA/cm2 at the proximal femur. These values were greatly reduced in the women with anorexia nervosa to 0·77 gHA/cm2 and 0·65 gHA/cm2 respectively (P<0·01). Our findings confirm the loss of bone mass with anorexia and demonstrate the coexistent loss of skin thickness and skin collagen content. This association supports the hypothesis that a generalized loss of collagen is a major factor in the causation of osteoporosis following oestrogen deficiency." @default.
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- W2005374674 date "1989-12-01" @default.
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- W2005374674 title "The effect of anorexia nervosa on skin thickness, skin collagen and bone density" @default.
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- W2005374674 doi "https://doi.org/10.1111/j.1471-0528.1989.tb06300.x" @default.
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