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- W2005378502 abstract "Of the many types of DNA-damage repair, this review concentrates on the aspects of DNA single- and double-strand break repair. Originally considered to represent separate routes based on distinct enzymatic machineries, it has recently been shown that these pathways converge and are interlinked at a number of points. Poly(ADP-ribose) polymerase-1 (PARP-1) is a central player in this complicated game. We present new data and our view on the mechanisms by which PARP-1 is guided to its respective interaction partners to coordinate or participate in repair or apoptosis." @default.
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- W2005378502 date "2005-06-01" @default.
- W2005378502 modified "2023-10-10" @default.
- W2005378502 title "DNA break repair: refined rules of an already complicated game" @default.
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- W2005378502 doi "https://doi.org/10.1139/o05-044" @default.
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