FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005379110> ?p ?o ?g. }

• W2005379110 endingPage "624" @default.
• W2005379110 startingPage "614" @default.
• W2005379110 abstract "Abstract Large‐scale commercialization of baculovirus biopesticides for the control of insect pests requires a cell culture production process, and knowledge of the infection kinetics is a vital prerequisite for process optimization. Well‐characterized kinetic parameters have so far only been reported for the commercially established recombinant Autographa californica nucleopolyhedrovirus (AcMNPV), a Group I NPV. In this work, key infection kinetic parameters of the Group II NPV Helicoverpa armigera nucleopolyhedrovirus (HaSNPV), and its Few Polyhedra (FP) mutant, were well characterized for the first time, in suspension HzAM1 insect cell cultures, to facilitate the scale‐up of an HaSNPV‐based biopesticide. The FP mutant had a selective advantage over wild‐type HaSNPV in cell cultures, and the kinetic analysis showed that this was due to a superior budding rate, rather than a faster binding rate (BR) or longer budding duration. Another finding was that wild‐type HaSNPV had very poor infection kinetics when compared with AcMNPV, exhibiting an 18‐fold lower BR, a more than 50‐fold lower budding rate, and a 60‐fold lower extracellular/total progeny virus ratio. Such poor infection kinetics have serious implications during scale‐up of an HaSNPV biopesticide production process, including the requirement for large volumes of virus inocula and the difficulty of achieving synchronous infections. Groups I and II NPVs may have very different infection kinetics because of their different envelope fusion proteins. This study is the first to compare the two groups of NPVs in terms of well‐characterized cell‐specific infection kinetics, and the findings may indicate a phylogenetic basis for kinetic differences. © 2011 American Institute of Chemical Engineers Biotechnol. Prog., 2011" @default.
• W2005379110 created "2016-06-24" @default.
• W2005379110 creator A5022734889 @default.
• W2005379110 creator A5045470419 @default.
• W2005379110 creator A5061172047 @default.
• W2005379110 creator A5072663242 @default.
• W2005379110 date "2011-04-19" @default.
• W2005379110 modified "2023-10-16" @default.
• W2005379110 title "Kinetic characterization of the group II helicoverpa armigera nucleopolyhedrovirus propagated in suspension cell cultures: Implications for development of a biopesticides production process" @default.
• W2005379110 cites W1585330735 @default.
• W2005379110 cites W1861740404 @default.
• W2005379110 cites W1897069665 @default.
• W2005379110 cites W1971786479 @default.
• W2005379110 cites W1976341978 @default.
• W2005379110 cites W1982225977 @default.
• W2005379110 cites W1984406334 @default.
• W2005379110 cites W1986154134 @default.
• W2005379110 cites W1990537991 @default.
• W2005379110 cites W1998537145 @default.
• W2005379110 cites W1999150301 @default.
• W2005379110 cites W2001155691 @default.
• W2005379110 cites W2001805029 @default.
• W2005379110 cites W2011034048 @default.
• W2005379110 cites W2011284066 @default.
• W2005379110 cites W2023908850 @default.
• W2005379110 cites W2028706407 @default.
• W2005379110 cites W2031910333 @default.
• W2005379110 cites W2034417219 @default.
• W2005379110 cites W2038493876 @default.
• W2005379110 cites W2048588124 @default.
• W2005379110 cites W2050717010 @default.
• W2005379110 cites W2057909529 @default.
• W2005379110 cites W2063460869 @default.
• W2005379110 cites W2068175060 @default.
• W2005379110 cites W2070879001 @default.
• W2005379110 cites W2073545911 @default.
• W2005379110 cites W2075800302 @default.
• W2005379110 cites W2085352587 @default.
• W2005379110 cites W2087308055 @default.
• W2005379110 cites W2087944963 @default.
• W2005379110 cites W2089536471 @default.
• W2005379110 cites W2089772918 @default.
• W2005379110 cites W2093433620 @default.
• W2005379110 cites W2101632670 @default.
• W2005379110 cites W2107661572 @default.
• W2005379110 cites W2114800997 @default.
• W2005379110 cites W2116005117 @default.
• W2005379110 cites W2116480459 @default.
• W2005379110 cites W2118832701 @default.
• W2005379110 cites W2119909782 @default.
• W2005379110 cites W2127865821 @default.
• W2005379110 cites W2131335594 @default.
• W2005379110 cites W2135634224 @default.
• W2005379110 cites W2135682000 @default.
• W2005379110 cites W2137537220 @default.
• W2005379110 cites W2140836172 @default.
• W2005379110 cites W2146213942 @default.
• W2005379110 cites W2149229942 @default.
• W2005379110 cites W2170641144 @default.
• W2005379110 cites W2175553381 @default.
• W2005379110 cites W2175802407 @default.
• W2005379110 cites W2200288427 @default.
• W2005379110 cites W2202085416 @default.
• W2005379110 doi "https://doi.org/10.1002/btpr.602" @default.
• W2005379110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21644255" @default.
• W2005379110 hasPublicationYear "2011" @default.
• W2005379110 type Work @default.
• W2005379110 sameAs 2005379110 @default.
• W2005379110 citedByCount "16" @default.
• W2005379110 countsByYear W20053791102012 @default.
• W2005379110 countsByYear W20053791102013 @default.
• W2005379110 countsByYear W20053791102014 @default.
• W2005379110 countsByYear W20053791102015 @default.
• W2005379110 countsByYear W20053791102016 @default.
• W2005379110 countsByYear W20053791102017 @default.
• W2005379110 countsByYear W20053791102019 @default.
• W2005379110 countsByYear W20053791102023 @default.
• W2005379110 crossrefType "journal-article" @default.
• W2005379110 hasAuthorship W2005379110A5022734889 @default.
• W2005379110 hasAuthorship W2005379110A5045470419 @default.
• W2005379110 hasAuthorship W2005379110A5061172047 @default.
• W2005379110 hasAuthorship W2005379110A5072663242 @default.
• W2005379110 hasConcept C104317684 @default.
• W2005379110 hasConcept C120835403 @default.
• W2005379110 hasConcept C143065580 @default.
• W2005379110 hasConcept C159047783 @default.
• W2005379110 hasConcept C161176658 @default.
• W2005379110 hasConcept C177756618 @default.
• W2005379110 hasConcept C198410946 @default.
• W2005379110 hasConcept C2776712339 @default.
• W2005379110 hasConcept C2777212814 @default.
• W2005379110 hasConcept C2777773057 @default.
• W2005379110 hasConcept C2778551188 @default.
• W2005379110 hasConcept C2780199244 @default.
• W2005379110 hasConcept C40767141 @default.
• W2005379110 hasConcept C54355233 @default.
• W2005379110 hasConcept C59822182 @default.
• W2005379110 hasConcept C6557445 @default.

• next