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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005393048> ?p ?o ?g. }

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• W2005393048 abstract "We cloned a major isoform of Xenopus homologue of cold inducible RNA binding protein (CIRP), XCIRP-1. XCIRP-1 was neither cold inducible nor essential for cell division during early embryonic development. Suppression of XCIRP-1 dose dependently produced tailbuds with deformations of the brain and internal organs. The defects were XCIRP-1 specific as they could be rescued by sense transcript. Suppression of XCIRP-1 also disrupted the morphogenetic migration of the C3 blastomeres (lineaged to become the embryonic kidney, the pronephros). In animal cap explants, depletion of XCIRP-1 inhibited activin/retinoic acid induced expressions of pronephros related Xlim-1 and WT1 genes. These results suggest that XCIRP-1 is required for the specification and morphogenetic lineage migration of the pronephros." @default.
• W2005393048 created "2016-06-24" @default.
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• W2005393048 date "2000-09-28" @default.
• W2005393048 modified "2023-09-30" @default.
• W2005393048 title "Maternal cold inducible RNA binding protein is required for embryonic kidney formation in<i>Xenopus laevis</i>" @default.
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• W2005393048 doi "https://doi.org/10.1016/s0014-5793(00)02019-6" @default.
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