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- W2005394095 abstract "Premature infants lack the vernix caseosa, have an incompetent stratum corneum (SC) barrier and are predisposed to infection. Use of topical agents to improve barrier function has had mixed outcomes. The aim was to determine the effect of vernix versus common barrier creams on the rate and quality of the epidermal barrier repair following controlled wounding.Minor wounds were created with (1) laser ablation in the minipig and (2) tape stripping of mother's volar skin as a model for premature skin. Native vernix was applied to the mother's tape-stripped skin. Treatments were no occlusion (NO), vernix and a petrolatum-based cream (PBC) in the pig, and NO, vernix, PBC, an oil-in-water cream (OWC), a semipermeable film (SP) and full occlusion (FO) in adults.Outcomes for both trials were barrier recovery and skin hydration (moisture accumulation rate, MAT), initial hydration, erythema and dryness in adults. Vernix and PBC produced greater barrier repair than NO in the pig. SP produced greater recovery than NO and FO in adults. Vernix yielded greater recovery than FO and was similar to PBC, OWC and NO. Vernix had a directionally higher MAT than OWC and directionally higher initial hydration than NO.The findings suggest that vernix-based topical creams would be effective for the treatment of epidermal wounds and show promise to augment SC repair and maturation in infants." @default.
- W2005394095 created "2016-06-24" @default.
- W2005394095 creator A5008118686 @default.
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- W2005394095 creator A5071632531 @default.
- W2005394095 creator A5073296715 @default.
- W2005394095 date "2011-01-01" @default.
- W2005394095 modified "2023-10-18" @default.
- W2005394095 title "Epidermal Barrier Treatments Based on Vernix Caseosa" @default.
- W2005394095 cites W1212382431 @default.
- W2005394095 cites W1485914854 @default.
- W2005394095 cites W1494923852 @default.
- W2005394095 cites W1530053640 @default.
- W2005394095 cites W1851966488 @default.
- W2005394095 cites W1964717063 @default.
- W2005394095 cites W1965468909 @default.
- W2005394095 cites W1971992928 @default.
- W2005394095 cites W1974172719 @default.
- W2005394095 cites W1974511893 @default.
- W2005394095 cites W1976541727 @default.
- W2005394095 cites W1976620131 @default.
- W2005394095 cites W1977846688 @default.
- W2005394095 cites W1978297226 @default.
- W2005394095 cites W1978547603 @default.
- W2005394095 cites W1983946860 @default.
- W2005394095 cites W1984347303 @default.
- W2005394095 cites W1985360603 @default.
- W2005394095 cites W1992039191 @default.
- W2005394095 cites W1996392766 @default.
- W2005394095 cites W1996592974 @default.
- W2005394095 cites W1996940153 @default.
- W2005394095 cites W2009634118 @default.
- W2005394095 cites W2010648873 @default.
- W2005394095 cites W2012801014 @default.
- W2005394095 cites W2013155523 @default.
- W2005394095 cites W2014970771 @default.
- W2005394095 cites W2015139086 @default.
- W2005394095 cites W2018673693 @default.
- W2005394095 cites W2019829957 @default.
- W2005394095 cites W2020831130 @default.
- W2005394095 cites W2022099002 @default.
- W2005394095 cites W2022244556 @default.
- W2005394095 cites W2027386197 @default.
- W2005394095 cites W2028011317 @default.
- W2005394095 cites W2035912309 @default.
- W2005394095 cites W2036556443 @default.
- W2005394095 cites W2037615932 @default.
- W2005394095 cites W2039896571 @default.
- W2005394095 cites W2044364035 @default.
- W2005394095 cites W2045098982 @default.
- W2005394095 cites W2047550548 @default.
- W2005394095 cites W2049593244 @default.
- W2005394095 cites W2057314334 @default.
- W2005394095 cites W2058964528 @default.
- W2005394095 cites W2060277900 @default.
- W2005394095 cites W2061708976 @default.
- W2005394095 cites W2062277825 @default.
- W2005394095 cites W2067106467 @default.
- W2005394095 cites W2067204579 @default.
- W2005394095 cites W2067885488 @default.
- W2005394095 cites W2074343451 @default.
- W2005394095 cites W2077055924 @default.
- W2005394095 cites W2084120842 @default.
- W2005394095 cites W2086818465 @default.
- W2005394095 cites W2091422866 @default.
- W2005394095 cites W2091974829 @default.
- W2005394095 cites W2092132643 @default.
- W2005394095 cites W2096202358 @default.
- W2005394095 cites W2097754683 @default.
- W2005394095 cites W2102560852 @default.
- W2005394095 cites W2104571834 @default.
- W2005394095 cites W2111634753 @default.
- W2005394095 cites W2121714856 @default.
- W2005394095 cites W2123308506 @default.
- W2005394095 cites W2124226100 @default.
- W2005394095 cites W2124255446 @default.
- W2005394095 cites W2125399875 @default.
- W2005394095 cites W2129393221 @default.
- W2005394095 cites W2133341882 @default.
- W2005394095 cites W2135693586 @default.
- W2005394095 cites W2142384326 @default.
- W2005394095 cites W2156071020 @default.
- W2005394095 cites W2166318165 @default.
- W2005394095 cites W2166328817 @default.
- W2005394095 cites W2170111304 @default.
- W2005394095 cites W2224846218 @default.
- W2005394095 cites W2404681272 @default.
- W2005394095 cites W245689918 @default.
- W2005394095 cites W2460818474 @default.
- W2005394095 cites W2601458797 @default.
- W2005394095 cites W2994137882 @default.
- W2005394095 cites W3026209465 @default.
- W2005394095 cites W2075587030 @default.
- W2005394095 doi "https://doi.org/10.1159/000328744" @default.
- W2005394095 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21822033" @default.
- W2005394095 hasPublicationYear "2011" @default.