FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005397767> ?p ?o ?g. }

• W2005397767 endingPage "1036" @default.
• W2005397767 startingPage "1028" @default.
• W2005397767 abstract "BACKGROUND Long term results after liver resection for hepatocellular carcinoma (HCC) are disappointing because the disease tends to recur. In this study, the authors assessed prognostic factors affecting long term outcome, in the hope that these factors might be used in selecting HCC patients for surgery. METHODS During the period 1977-1995, 100 consecutive patients underwent curative liver resection; 78 of 100 had HCC arising on preexisting cirrhosis (53 Child's Class A and 25 Child's Class B). Thirty-five prognostic factors were evaluated for their association with overall survival (OS) and disease free survival (DFS) in univariate and multivariate analysis (Cox proportional hazards model). RESULTS There were four postoperative deaths. Seven patients died in hospital of hepatorenal failure: six had Child's Class B cirrhosis and had undergone preoperative chemoembolization. Of the remaining 89 patients, 50 developed recurrence. All surviving Child's Class B patients had recurrence. Five-year OS, postoperative deaths included, was 38% (median, 36 months). Five-year DFS, postoperative deaths excluded, was 26% (median, 21 months). Independent prognostic factors for DFS were Child's class, glutamic-oxaloacetic transaminase, γ-glutamyltransferase, α-fetoprotein, number of tumor nodules, width of resection margins, preoperative chemoembolization, and experience of the team that performed the surgery. Factors with an independent effect on OS were Child's class and width of resection margins. CONCLUSIONS Liver resection can provide long term DFS in HCC patients with normal liver function. In patients with liver function impairment or an inadequate resection margin, recurrences are almost certain to occur. Preoperative chemoembolization significantly prolongs DFS but may increase the risk of postoperative liver failure in patients with liver function impairment. Cancer 1998;82:1028-36. © 1998 American Cancer Society." @default.
• W2005397767 created "2016-06-24" @default.
• W2005397767 creator A5006180344 @default.
• W2005397767 creator A5007107429 @default.
• W2005397767 creator A5010324991 @default.
• W2005397767 creator A5020725018 @default.
• W2005397767 creator A5041363340 @default.
• W2005397767 creator A5088759342 @default.
• W2005397767 date "1998-03-15" @default.
• W2005397767 modified "2023-10-17" @default.
• W2005397767 title "Prognostic factors affecting long term outcome after liver resection for hepatocellular carcinoma" @default.
• W2005397767 cites W1562772349 @default.
• W2005397767 cites W1963668453 @default.
• W2005397767 cites W1977268696 @default.
• W2005397767 cites W1986414102 @default.
• W2005397767 cites W1986651745 @default.
• W2005397767 cites W1987978415 @default.
• W2005397767 cites W1989485732 @default.
• W2005397767 cites W1994692529 @default.
• W2005397767 cites W1995290931 @default.
• W2005397767 cites W2005233065 @default.
• W2005397767 cites W2012707575 @default.
• W2005397767 cites W2014353310 @default.
• W2005397767 cites W2021309978 @default.
• W2005397767 cites W2032897438 @default.
• W2005397767 cites W2033538224 @default.
• W2005397767 cites W2037245133 @default.
• W2005397767 cites W2041365562 @default.
• W2005397767 cites W2056527566 @default.
• W2005397767 cites W2065726661 @default.
• W2005397767 cites W2068046495 @default.
• W2005397767 cites W2071841994 @default.
• W2005397767 cites W2073613118 @default.
• W2005397767 cites W2087211983 @default.
• W2005397767 cites W2089241402 @default.
• W2005397767 cites W2093986504 @default.
• W2005397767 cites W2095523020 @default.
• W2005397767 cites W2099534259 @default.
• W2005397767 cites W2144760355 @default.
• W2005397767 cites W2315027248 @default.
• W2005397767 cites W2412404459 @default.
• W2005397767 cites W3140151417 @default.
• W2005397767 cites W91534136 @default.
• W2005397767 doi "https://doi.org/10.1002/(sici)1097-0142(19980315)82:6<1028::aid-cncr4>3.0.co;2-a" @default.
• W2005397767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9506346" @default.
• W2005397767 hasPublicationYear "1998" @default.
• W2005397767 type Work @default.
• W2005397767 sameAs 2005397767 @default.
• W2005397767 citedByCount "150" @default.
• W2005397767 countsByYear W20053977672012 @default.
• W2005397767 countsByYear W20053977672013 @default.
• W2005397767 countsByYear W20053977672014 @default.
• W2005397767 countsByYear W20053977672015 @default.
• W2005397767 countsByYear W20053977672016 @default.
• W2005397767 countsByYear W20053977672017 @default.
• W2005397767 countsByYear W20053977672018 @default.
• W2005397767 countsByYear W20053977672020 @default.
• W2005397767 countsByYear W20053977672021 @default.
• W2005397767 countsByYear W20053977672022 @default.
• W2005397767 countsByYear W20053977672023 @default.
• W2005397767 crossrefType "journal-article" @default.
• W2005397767 hasAuthorship W2005397767A5006180344 @default.
• W2005397767 hasAuthorship W2005397767A5007107429 @default.
• W2005397767 hasAuthorship W2005397767A5010324991 @default.
• W2005397767 hasAuthorship W2005397767A5020725018 @default.
• W2005397767 hasAuthorship W2005397767A5041363340 @default.
• W2005397767 hasAuthorship W2005397767A5088759342 @default.
• W2005397767 hasBestOaLocation W20053977671 @default.
• W2005397767 hasConcept C126322002 @default.
• W2005397767 hasConcept C141071460 @default.
• W2005397767 hasConcept C144301174 @default.
• W2005397767 hasConcept C159110652 @default.
• W2005397767 hasConcept C2776909242 @default.
• W2005397767 hasConcept C2777214474 @default.
• W2005397767 hasConcept C2778019345 @default.
• W2005397767 hasConcept C2992208098 @default.
• W2005397767 hasConcept C38180746 @default.
• W2005397767 hasConcept C50382708 @default.
• W2005397767 hasConcept C71924100 @default.
• W2005397767 hasConcept C90924648 @default.
• W2005397767 hasConceptScore W2005397767C126322002 @default.
• W2005397767 hasConceptScore W2005397767C141071460 @default.
• W2005397767 hasConceptScore W2005397767C144301174 @default.
• W2005397767 hasConceptScore W2005397767C159110652 @default.
• W2005397767 hasConceptScore W2005397767C2776909242 @default.
• W2005397767 hasConceptScore W2005397767C2777214474 @default.
• W2005397767 hasConceptScore W2005397767C2778019345 @default.
• W2005397767 hasConceptScore W2005397767C2992208098 @default.
• W2005397767 hasConceptScore W2005397767C38180746 @default.
• W2005397767 hasConceptScore W2005397767C50382708 @default.
• W2005397767 hasConceptScore W2005397767C71924100 @default.
• W2005397767 hasConceptScore W2005397767C90924648 @default.
• W2005397767 hasIssue "6" @default.
• W2005397767 hasLocation W20053977671 @default.
• W2005397767 hasLocation W20053977672 @default.
• W2005397767 hasOpenAccess W2005397767 @default.
• W2005397767 hasPrimaryLocation W20053977671 @default.
• W2005397767 hasRelatedWork W1978128124 @default.

• next