Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005403824> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2005403824 endingPage "1422" @default.
- W2005403824 startingPage "1417" @default.
- W2005403824 abstract "For estimation of human exposures to carcinogenic heterocyclic amines, the amounts of four compounds, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1), 3-amino-1- methyl-5H-pyrido[4,3-b]indole (Trp-P-2), 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 2-amlno-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), in human urine were measured. Twenty-four hour urine specimens were collected from ten healthy volunteers eating normal diet (five males and five females) and three inpatlents (two males and a female) receiving parenteral alimentation, and the levels of the four heterocydic amines were measured by HPLC after partial purification by treatment with blue cotton and ion exchange column chromatography. Trp-P-1, Trp-P-2, PhIP and MeIQx were detected in the 24 h urine samples of all healthy volunteers at levels of 0.04–1.43 ng, 0.03–0.68 ng, 0.12–1.97 ng and 11–47 ng respectively. As 1.8–4.9% of an oral dose of MeIQx is reported to be excreted unchanged in the urine, the daily exposure of humans to MeIQx was estimated to be 0.2–2.6 μg/person. The four heterocyclic amines were not detected in the urine of parenterally fed inpatients. These results indicate that humans are continually exposed to carcinogenic heterocydlic amines in food, and these compounds may not be formed endogenously." @default.
- W2005403824 created "2016-06-24" @default.
- W2005403824 creator A5000409879 @default.
- W2005403824 creator A5045339298 @default.
- W2005403824 creator A5063644416 @default.
- W2005403824 creator A5064650618 @default.
- W2005403824 creator A5071203568 @default.
- W2005403824 creator A5075371239 @default.
- W2005403824 date "1991-01-01" @default.
- W2005403824 modified "2023-10-10" @default.
- W2005403824 title "Presence of carcinogenic heterocyclic amines in urine of healthy volunteers eating normal diet, but not of inpatients receiving parenteral alimentation" @default.
- W2005403824 doi "https://doi.org/10.1093/carcin/12.8.1417" @default.
- W2005403824 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1907222" @default.
- W2005403824 hasPublicationYear "1991" @default.
- W2005403824 type Work @default.
- W2005403824 sameAs 2005403824 @default.
- W2005403824 citedByCount "177" @default.
- W2005403824 countsByYear W20054038242012 @default.
- W2005403824 countsByYear W20054038242013 @default.
- W2005403824 countsByYear W20054038242015 @default.
- W2005403824 countsByYear W20054038242016 @default.
- W2005403824 countsByYear W20054038242017 @default.
- W2005403824 countsByYear W20054038242019 @default.
- W2005403824 countsByYear W20054038242021 @default.
- W2005403824 countsByYear W20054038242022 @default.
- W2005403824 crossrefType "journal-article" @default.
- W2005403824 hasAuthorship W2005403824A5000409879 @default.
- W2005403824 hasAuthorship W2005403824A5045339298 @default.
- W2005403824 hasAuthorship W2005403824A5063644416 @default.
- W2005403824 hasAuthorship W2005403824A5064650618 @default.
- W2005403824 hasAuthorship W2005403824A5071203568 @default.
- W2005403824 hasAuthorship W2005403824A5075371239 @default.
- W2005403824 hasConcept C114246631 @default.
- W2005403824 hasConcept C126322002 @default.
- W2005403824 hasConcept C134018914 @default.
- W2005403824 hasConcept C178790620 @default.
- W2005403824 hasConcept C185592680 @default.
- W2005403824 hasConcept C192527728 @default.
- W2005403824 hasConcept C2776639595 @default.
- W2005403824 hasConcept C2777278644 @default.
- W2005403824 hasConcept C2778818824 @default.
- W2005403824 hasConcept C2780026642 @default.
- W2005403824 hasConcept C2780362310 @default.
- W2005403824 hasConcept C55493867 @default.
- W2005403824 hasConcept C71924100 @default.
- W2005403824 hasConceptScore W2005403824C114246631 @default.
- W2005403824 hasConceptScore W2005403824C126322002 @default.
- W2005403824 hasConceptScore W2005403824C134018914 @default.
- W2005403824 hasConceptScore W2005403824C178790620 @default.
- W2005403824 hasConceptScore W2005403824C185592680 @default.
- W2005403824 hasConceptScore W2005403824C192527728 @default.
- W2005403824 hasConceptScore W2005403824C2776639595 @default.
- W2005403824 hasConceptScore W2005403824C2777278644 @default.
- W2005403824 hasConceptScore W2005403824C2778818824 @default.
- W2005403824 hasConceptScore W2005403824C2780026642 @default.
- W2005403824 hasConceptScore W2005403824C2780362310 @default.
- W2005403824 hasConceptScore W2005403824C55493867 @default.
- W2005403824 hasConceptScore W2005403824C71924100 @default.
- W2005403824 hasIssue "8" @default.
- W2005403824 hasLocation W20054038241 @default.
- W2005403824 hasLocation W20054038242 @default.
- W2005403824 hasOpenAccess W2005403824 @default.
- W2005403824 hasPrimaryLocation W20054038241 @default.
- W2005403824 hasRelatedWork W1987298730 @default.
- W2005403824 hasRelatedWork W1990754623 @default.
- W2005403824 hasRelatedWork W1998869070 @default.
- W2005403824 hasRelatedWork W2080456042 @default.
- W2005403824 hasRelatedWork W2147324381 @default.
- W2005403824 hasRelatedWork W2162607493 @default.
- W2005403824 hasRelatedWork W2317445279 @default.
- W2005403824 hasRelatedWork W2949935065 @default.
- W2005403824 hasRelatedWork W566726338 @default.
- W2005403824 hasRelatedWork W578894405 @default.
- W2005403824 hasVolume "12" @default.
- W2005403824 isParatext "false" @default.
- W2005403824 isRetracted "false" @default.
- W2005403824 magId "2005403824" @default.
- W2005403824 workType "article" @default.