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- W2005431185 abstract "<h3>To the Editor.—</h3> Systemic meningococcal infections are presumed to follow spread of meningococci from the nasopharynx into the blood and then to the cerebrospinal fluid.<sup>1</sup>However, there have been reports of at least 10 cases of systemic meningococcal infection in which the conjunctiva was the probable portal of entry.<sup>2-11</sup>The overall incidence of invasive meningococcal conjunctivitis has been estimated to be about 10% of the cases of primary meningococcal conjunctivitis.<sup>12</sup> <i>Neisseria meningitidis</i>was isolated from conjunctival exudate in 21 patients with acute bacterial conjunctivitis who were treated at our hospital during the last 5 years. During this period, 1030 patients with a microbiologically proved acute bacterial conjunctivitis were diagnosed, which gives an incidence for<i>N meningitidis</i>conjunctivitis of 2.0%. Six (28.6%) of our 21 patients with primary meningococcal conjunctivitis, after a mean interval of 27.1 (±23.8) hours from the appearance of the initial ocular symptoms, developed systemic" @default.
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- W2005431185 date "1990-07-18" @default.
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- W2005431185 title "Invasive Meningococcal Conjunctivitis" @default.
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- W2005431185 doi "https://doi.org/10.1001/jama.1990.03450030049014" @default.
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