Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005436183> ?p ?o ?g. }
- W2005436183 endingPage "102" @default.
- W2005436183 startingPage "89" @default.
- W2005436183 abstract "Retinitis pigmentosa refers to a family of hereditary retinal degenerations that lead to photoreceptor death and vision loss. The underlying cause(s) are not known. In recent years there has been accumulating evidence of neurochemical changes during degeneration. In particular, the amino acids glutamate, GABA, and glycine show alterations in labelling intensity in subsets of neurons. Furthermore, there are differences in the labelling of the precursors, glutamine and aspartate, prior to, during, and following loss of photoreceptors, suggesting that the metabolic pathways involved in neurotransmitter formation and degradation may be abnormal. In addition, there is an elevation in glutamine and arginine content within Müller cells prior to the onset of photoreceptor death. Investigations evaluating Müller cell function indicate that formation and degradation of glutamate, in particular, is abnormal in the degenerating retina from an early age. These studies suggest that even though the primary genetic defect of the RCS rat is within the retinal pigment epithelium, Müller cells develop abnormally, and may contribute to the observed photoreceptor loss. Microsc. Res. Tech. 50:89–102, 2000. © 2000 Wiley-Liss, Inc." @default.
- W2005436183 created "2016-06-24" @default.
- W2005436183 creator A5048943367 @default.
- W2005436183 date "2000-01-01" @default.
- W2005436183 modified "2023-10-11" @default.
- W2005436183 title "Alterations in neurochemistry during retinal degeneration" @default.
- W2005436183 cites W1484547529 @default.
- W2005436183 cites W1499343644 @default.
- W2005436183 cites W1515271298 @default.
- W2005436183 cites W1549420378 @default.
- W2005436183 cites W1588159686 @default.
- W2005436183 cites W1600687240 @default.
- W2005436183 cites W1890868908 @default.
- W2005436183 cites W1924525922 @default.
- W2005436183 cites W1934020811 @default.
- W2005436183 cites W1964434209 @default.
- W2005436183 cites W1968369052 @default.
- W2005436183 cites W1980442975 @default.
- W2005436183 cites W1982677353 @default.
- W2005436183 cites W1983185397 @default.
- W2005436183 cites W1984491380 @default.
- W2005436183 cites W1984977607 @default.
- W2005436183 cites W1990015532 @default.
- W2005436183 cites W1992792117 @default.
- W2005436183 cites W1993692154 @default.
- W2005436183 cites W1996023277 @default.
- W2005436183 cites W1999612489 @default.
- W2005436183 cites W2002598925 @default.
- W2005436183 cites W2003922790 @default.
- W2005436183 cites W2011886504 @default.
- W2005436183 cites W2013220475 @default.
- W2005436183 cites W201363424 @default.
- W2005436183 cites W2018161463 @default.
- W2005436183 cites W2019341469 @default.
- W2005436183 cites W2021124272 @default.
- W2005436183 cites W2022618565 @default.
- W2005436183 cites W2029624481 @default.
- W2005436183 cites W2034845337 @default.
- W2005436183 cites W2041437797 @default.
- W2005436183 cites W2043057314 @default.
- W2005436183 cites W2043985651 @default.
- W2005436183 cites W2054329327 @default.
- W2005436183 cites W2054575022 @default.
- W2005436183 cites W2056306332 @default.
- W2005436183 cites W2059813760 @default.
- W2005436183 cites W2059861277 @default.
- W2005436183 cites W2061068333 @default.
- W2005436183 cites W2065553981 @default.
- W2005436183 cites W2066829458 @default.
- W2005436183 cites W2067438800 @default.
- W2005436183 cites W2071540714 @default.
- W2005436183 cites W2074968619 @default.
- W2005436183 cites W2080678410 @default.
- W2005436183 cites W2083557125 @default.
- W2005436183 cites W2088103373 @default.
- W2005436183 cites W2093889618 @default.
- W2005436183 cites W2095242545 @default.
- W2005436183 cites W2122345966 @default.
- W2005436183 cites W2126577146 @default.
- W2005436183 cites W2152272038 @default.
- W2005436183 cites W2156269367 @default.
- W2005436183 cites W2156386407 @default.
- W2005436183 cites W2163153417 @default.
- W2005436183 cites W2172549145 @default.
- W2005436183 cites W4300900670 @default.
- W2005436183 doi "https://doi.org/10.1002/1097-0029(20000715)50:2<89::aid-jemt1>3.0.co;2-9" @default.
- W2005436183 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10891873" @default.
- W2005436183 hasPublicationYear "2000" @default.
- W2005436183 type Work @default.
- W2005436183 sameAs 2005436183 @default.
- W2005436183 citedByCount "23" @default.
- W2005436183 countsByYear W20054361832012 @default.
- W2005436183 countsByYear W20054361832013 @default.
- W2005436183 countsByYear W20054361832015 @default.
- W2005436183 countsByYear W20054361832016 @default.
- W2005436183 countsByYear W20054361832018 @default.
- W2005436183 countsByYear W20054361832022 @default.
- W2005436183 crossrefType "journal-article" @default.
- W2005436183 hasAuthorship W2005436183A5048943367 @default.
- W2005436183 hasConcept C118487528 @default.
- W2005436183 hasConcept C142724271 @default.
- W2005436183 hasConcept C169760540 @default.
- W2005436183 hasConcept C170493617 @default.
- W2005436183 hasConcept C190283241 @default.
- W2005436183 hasConcept C25876315 @default.
- W2005436183 hasConcept C2776219046 @default.
- W2005436183 hasConcept C2776403814 @default.
- W2005436183 hasConcept C2777093970 @default.
- W2005436183 hasConcept C2778024200 @default.
- W2005436183 hasConcept C2779349466 @default.
- W2005436183 hasConcept C2779354088 @default.
- W2005436183 hasConcept C2780827179 @default.
- W2005436183 hasConcept C2781040256 @default.
- W2005436183 hasConcept C2781114197 @default.
- W2005436183 hasConcept C31573885 @default.
- W2005436183 hasConcept C515207424 @default.
- W2005436183 hasConcept C529278444 @default.
- W2005436183 hasConcept C55493867 @default.