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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005448981> ?p ?o ?g. }

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• W2005448981 abstract "We report the identification of KD5170, a potent mercaptoketone-based Class I and II-histone deacetylase inhibitor that demonstrates broad spectrum cytotoxic activity against a range of human tumor-derived cell lines. KD5170 exhibits robust and sustained histone H3 hyperacetylation in HCT-116 xenograft tumors following single oral or iv dose and inhibition of tumor growth following chronic dosing." @default.
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• W2005448981 date "2008-12-01" @default.
• W2005448981 modified "2023-10-03" @default.
• W2005448981 title "Identification of KD5170: A novel mercaptoketone-based histone deacetylase inhibitor" @default.
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• W2005448981 doi "https://doi.org/10.1016/j.bmcl.2008.10.029" @default.
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