FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005454345> ?p ?o ?g. }

• W2005454345 endingPage "137" @default.
• W2005454345 startingPage "129" @default.
• W2005454345 abstract "We have studied the effects of adoptive transfer of host thymic dendritic cells pulsed with immunodominant WF Class I peptide 5 (residues 93–109) on cardiac allograft survival in the WF-to-ACI rat combination. Our results showed that, whereas intrathymic inoculation of WF peptide 5-pulsed ACI thymic dendritic cells alone on day −7 did not prolong graft survival, similar treatment combined with 0.5 mL antilymphocyte serum (ALS) led to 100% permanent acceptance (> 200 d) of donor-specific cardiac allografts. Extension of our study to systemic administration of peptide 5-pulsed host thymic dendritic cells confirmed that intravenous injection of peptide 5-pulsed self thymic dendritic cells combined with ALS transient immunosuppression resulted in 100% permanent donor-specific graft survival (> 200 d). These results were reproducible in a clinically relevant model using intravenous injection of peptide-pulsed host myeloid dendritic cells. In contrast, thymectomy prior to adoptive transfer of peptide-pulsed host dendritic cells resulted in acute graft rejection at times equivalent to rejection in thymectomized controls. The long-term unresponsive recipients challenged with second-set grafts accepted permanently (> 100 d) donor-type (WF) but not third party (Lewis) cardiac allografts. This study suggests that intravenous administration of genetically engineered dendritic cells expressing donor MHC molecules has the potential of inducing transplant tolerance." @default.
• W2005454345 created "2016-06-24" @default.
• W2005454345 creator A5000969954 @default.
• W2005454345 creator A5022918963 @default.
• W2005454345 creator A5039940980 @default.
• W2005454345 creator A5046837142 @default.
• W2005454345 creator A5049101251 @default.
• W2005454345 creator A5076255347 @default.
• W2005454345 creator A5080048202 @default.
• W2005454345 date "2001-07-01" @default.
• W2005454345 modified "2023-09-23" @default.
• W2005454345 title "Induction of Transplant Tolerance with Immunodominant Allopeptide-pulsed Host Lymphoid and Myeloid Dendritic Cells" @default.
• W2005454345 cites W1515305163 @default.
• W2005454345 cites W1523435579 @default.
• W2005454345 cites W1553215445 @default.
• W2005454345 cites W1669105475 @default.
• W2005454345 cites W1830605513 @default.
• W2005454345 cites W1979041527 @default.
• W2005454345 cites W1982795412 @default.
• W2005454345 cites W1987053745 @default.
• W2005454345 cites W1992817263 @default.
• W2005454345 cites W1994425461 @default.
• W2005454345 cites W2003673506 @default.
• W2005454345 cites W2007362831 @default.
• W2005454345 cites W2014221405 @default.
• W2005454345 cites W2019522474 @default.
• W2005454345 cites W2039964292 @default.
• W2005454345 cites W2040326609 @default.
• W2005454345 cites W2046105249 @default.
• W2005454345 cites W2051502229 @default.
• W2005454345 cites W2057831214 @default.
• W2005454345 cites W2058026156 @default.
• W2005454345 cites W2063051740 @default.
• W2005454345 cites W2064139333 @default.
• W2005454345 cites W2064635028 @default.
• W2005454345 cites W2069279104 @default.
• W2005454345 cites W2073590360 @default.
• W2005454345 cites W2077389980 @default.
• W2005454345 cites W2078725645 @default.
• W2005454345 cites W2090500286 @default.
• W2005454345 cites W2091020747 @default.
• W2005454345 cites W2123832847 @default.
• W2005454345 cites W2132423677 @default.
• W2005454345 cites W2134211468 @default.
• W2005454345 cites W2138913424 @default.
• W2005454345 cites W2148647317 @default.
• W2005454345 cites W2161792071 @default.
• W2005454345 cites W2177327503 @default.
• W2005454345 cites W2402032625 @default.
• W2005454345 cites W4247261400 @default.
• W2005454345 cites W4313323075 @default.
• W2005454345 doi "https://doi.org/10.1034/j.1600-6143.2001.10206.x" @default.
• W2005454345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12099360" @default.
• W2005454345 hasPublicationYear "2001" @default.
• W2005454345 type Work @default.
• W2005454345 sameAs 2005454345 @default.
• W2005454345 citedByCount "65" @default.
• W2005454345 countsByYear W20054543452012 @default.
• W2005454345 countsByYear W20054543452013 @default.
• W2005454345 countsByYear W20054543452014 @default.
• W2005454345 countsByYear W20054543452016 @default.
• W2005454345 countsByYear W20054543452017 @default.
• W2005454345 countsByYear W20054543452018 @default.
• W2005454345 countsByYear W20054543452019 @default.
• W2005454345 countsByYear W20054543452022 @default.
• W2005454345 crossrefType "journal-article" @default.
• W2005454345 hasAuthorship W2005454345A5000969954 @default.
• W2005454345 hasAuthorship W2005454345A5022918963 @default.
• W2005454345 hasAuthorship W2005454345A5039940980 @default.
• W2005454345 hasAuthorship W2005454345A5046837142 @default.
• W2005454345 hasAuthorship W2005454345A5049101251 @default.
• W2005454345 hasAuthorship W2005454345A5076255347 @default.
• W2005454345 hasAuthorship W2005454345A5080048202 @default.
• W2005454345 hasBestOaLocation W20054543451 @default.
• W2005454345 hasConcept C126322002 @default.
• W2005454345 hasConcept C203014093 @default.
• W2005454345 hasConcept C2776090121 @default.
• W2005454345 hasConcept C2778170410 @default.
• W2005454345 hasConcept C2779193416 @default.
• W2005454345 hasConcept C2779282312 @default.
• W2005454345 hasConcept C2780252810 @default.
• W2005454345 hasConcept C2911091166 @default.
• W2005454345 hasConcept C71924100 @default.
• W2005454345 hasConcept C8891405 @default.
• W2005454345 hasConcept C90375314 @default.
• W2005454345 hasConceptScore W2005454345C126322002 @default.
• W2005454345 hasConceptScore W2005454345C203014093 @default.
• W2005454345 hasConceptScore W2005454345C2776090121 @default.
• W2005454345 hasConceptScore W2005454345C2778170410 @default.
• W2005454345 hasConceptScore W2005454345C2779193416 @default.
• W2005454345 hasConceptScore W2005454345C2779282312 @default.
• W2005454345 hasConceptScore W2005454345C2780252810 @default.
• W2005454345 hasConceptScore W2005454345C2911091166 @default.
• W2005454345 hasConceptScore W2005454345C71924100 @default.
• W2005454345 hasConceptScore W2005454345C8891405 @default.
• W2005454345 hasConceptScore W2005454345C90375314 @default.
• W2005454345 hasIssue "2" @default.
• W2005454345 hasLocation W20054543451 @default.

• next