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- W2005457174 abstract "This descriptive study investigates the genetic structure of seven Mexican indigenous populations (Mixteca Alta, Mixteca Baja, Otomies, Purepecha, Nahuas-Guerrero, Nahuas-Xochimilco, and Tzeltales) on the basis of five PCR-based polymorphic DNA loci: LDLR, GYPA, HBGG, D7S8, and GC. Genetic distance and diversity analyses indicate that these Mexican indigenous are similar and that more than 96% of the total gene diversity (H(T)) can be attributed to individual variation within populations. Mixteca-Alta, Mixteca-Baja, and Nahuas-Xochimilco show indications of higher admixture with European-derived persons. The demonstration of a relative genetic homogeneity of Mexican Indians for the markers studied suggests that this population is suitable for studying disease-marker associations in the search for candidate genes of complex diseases." @default.
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- W2005457174 date "2003-01-01" @default.
- W2005457174 modified "2023-10-16" @default.
- W2005457174 title "Genetic structure of seven Mexican indigenous populations based on five polymarker loci" @default.
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- W2005457174 doi "https://doi.org/10.1002/ajhb.10116" @default.
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