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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005463778> ?p ?o ?g. }

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• W2005463778 abstract "Eighteen volunteers in tow study groups were inoculated with influenza A (H3N2) and their peripheral blood T, B and null cells enumerated at subsequent intervals. Infection with wild-type virus or with a live, attenuated virus vaccine markedly reduced the proportion and absolute number of T-cell rosettes 24 hours after inoculation. T-Cell depression preceded the onset of clinical illness in symptomatic subjects, continued during illness, and returned to normal with recovery. T-cell lymphopenia was most pronounced in volunteers infected with wild-type virus and was accompanied by an increase in null cells. Lymphocytes from six wild-virus recipients with T-cell leukopenia were incubated in vitro with a calfthymus extract (thymosin), significantly increasing the percentage of T rosettes in all six subjects (P less than 0.0001). These data indicate that influenza is accompanied by pronounced quantitative and functional changes in T cells." @default.
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• W2005463778 date "1976-05-27" @default.
• W2005463778 modified "2023-10-16" @default.
• W2005463778 title "Influenza: Response of T-Cell Lymphopenia to Thymosin" @default.
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• W2005463778 doi "https://doi.org/10.1056/nejm197605272942204" @default.
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