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- W2005467079 abstract "Abstract Recently, it has been suggested that non‐classical antigens such as human leukocyte antigen (HLA)‐G and HLA‐E may interact with KIR receptors of NK cells which results into downregulation of immune response and helps in the maintenance of pregnancy. In the present study, we have investigated HLA‐E polymorphism in normal fertile women and recurrent spontaneous aborters to assess the effect of HLA‐E alleles on the success of pregnancy. Allele E*0101 was found to be significantly higher in patients with recurrent spontaneous abortion (χ 2 = 4.097 and P = 0.0430). Differential expression, peptide affinity, and stability of E*0101 may be one of the reasons." @default.
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- W2005467079 date "2006-03-01" @default.
- W2005467079 modified "2023-10-10" @default.
- W2005467079 title "HLA-E and immunobiology of pregnancy" @default.
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- W2005467079 doi "https://doi.org/10.1111/j.1399-0039.2005.00550.x" @default.
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