FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2005471831> ?p ?o ?g. }

• W2005471831 endingPage "1392" @default.
• W2005471831 startingPage "1387" @default.
• W2005471831 abstract "<h3>AIM</h3> To investigate the frequency, outcomes, and risk factors for acanthamoeba keratitis (AK) in England during the past 4 years. <h3>METHODS</h3> An ophthalmologist in 12 of the 14 regional health authorities (RHAs) coordinated identification of patients in their region presenting with AK between 1 October 1992 and 30 September 1996. Clinical and postal patient questionnaire data were analysed. <h3>RESULTS</h3> 243 patients (259 eyes) with an AK diagnosis were identified, equating to an annualised incidence of 0.14 per 100 000 individuals. UK resident patients for each year numbered 50, 71, 73, and 32 respectively. Among patients with sufficient data 170/237 (72%) were diagnosed early (within 30 days of presentation), 197/218 (90%) were treated with polyhexamethyl biguanide and/or chlorhexidine, and 40/243 (16%) underwent surgery. Visual acuities of 6/12 or better were achieved by 222/259 (86%) eyes, including 84 eyes of patients under review or lost to follow up. Non-contact lens (CL) wearers were associated with delayed diagnosis, increased need for surgery and a poorer visual outcome (only 10/18 eyes, 56%, achieved 6/12 acuity). 225/243 (93%) patients were CL wearers, and 205/243 (84%) were soft CL (SCL) users. Among SCL user respondents, previously identified risk factors—swimming with CL (47/138, 34%), non-sterile CL rinsing (11/138, 8%), omitted disinfection (85/138, 62%), and chlorine release disinfection (65/138, 47%)—were identified for 125/138 (91%) patients. <h3>CONCLUSIONS</h3> Earlier diagnosis and more effective medical therapy have improved the prognosis for most AK patients. The study demonstrates the highly preventable nature of the disease: 91% of the SCL wearers could have avoided the disease by refraining from inadvisable practices, and a marked fall in frequency was seen after intensive media attention to AK, possibly in conjunction with increasing penetrance of new CL products. Since the frequency of AK appears to be largely determined by the ever changing trends in CL use, continued monitoring is indicated." @default.
• W2005471831 created "2016-06-24" @default.
• W2005471831 creator A5012178445 @default.
• W2005471831 creator A5021917134 @default.
• W2005471831 creator A5036033001 @default.
• W2005471831 date "1998-12-01" @default.
• W2005471831 modified "2023-09-27" @default.
• W2005471831 title "Acanthamoeba keratitis: multicentre survey in England 1992-6" @default.
• W2005471831 cites W1606250061 @default.
• W2005471831 cites W175129026 @default.
• W2005471831 cites W1966526162 @default.
• W2005471831 cites W1983852682 @default.
• W2005471831 cites W1985990426 @default.
• W2005471831 cites W1996405783 @default.
• W2005471831 cites W2005597288 @default.
• W2005471831 cites W2007505324 @default.
• W2005471831 cites W2020637392 @default.
• W2005471831 cites W2022255920 @default.
• W2005471831 cites W2027944987 @default.
• W2005471831 cites W2035298927 @default.
• W2005471831 cites W2094087660 @default.
• W2005471831 cites W2212120594 @default.
• W2005471831 cites W2340219649 @default.
• W2005471831 cites W4290203426 @default.
• W2005471831 doi "https://doi.org/10.1136/bjo.82.12.1387" @default.
• W2005471831 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1722455" @default.
• W2005471831 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9930269" @default.
• W2005471831 hasPublicationYear "1998" @default.
• W2005471831 type Work @default.
• W2005471831 sameAs 2005471831 @default.
• W2005471831 citedByCount "201" @default.
• W2005471831 countsByYear W20054718312012 @default.
• W2005471831 countsByYear W20054718312013 @default.
• W2005471831 countsByYear W20054718312014 @default.
• W2005471831 countsByYear W20054718312015 @default.
• W2005471831 countsByYear W20054718312016 @default.
• W2005471831 countsByYear W20054718312017 @default.
• W2005471831 countsByYear W20054718312018 @default.
• W2005471831 countsByYear W20054718312019 @default.
• W2005471831 countsByYear W20054718312020 @default.
• W2005471831 countsByYear W20054718312021 @default.
• W2005471831 countsByYear W20054718312022 @default.
• W2005471831 countsByYear W20054718312023 @default.
• W2005471831 crossrefType "journal-article" @default.
• W2005471831 hasAuthorship W2005471831A5012178445 @default.
• W2005471831 hasAuthorship W2005471831A5021917134 @default.
• W2005471831 hasAuthorship W2005471831A5036033001 @default.
• W2005471831 hasBestOaLocation W20054718311 @default.
• W2005471831 hasConcept C118487528 @default.
• W2005471831 hasConcept C120665830 @default.
• W2005471831 hasConcept C121332964 @default.
• W2005471831 hasConcept C141071460 @default.
• W2005471831 hasConcept C187212893 @default.
• W2005471831 hasConcept C199343813 @default.
• W2005471831 hasConcept C2777084678 @default.
• W2005471831 hasConcept C2778257484 @default.
• W2005471831 hasConcept C2778560704 @default.
• W2005471831 hasConcept C2780576314 @default.
• W2005471831 hasConcept C2986805488 @default.
• W2005471831 hasConcept C61511704 @default.
• W2005471831 hasConcept C71924100 @default.
• W2005471831 hasConceptScore W2005471831C118487528 @default.
• W2005471831 hasConceptScore W2005471831C120665830 @default.
• W2005471831 hasConceptScore W2005471831C121332964 @default.
• W2005471831 hasConceptScore W2005471831C141071460 @default.
• W2005471831 hasConceptScore W2005471831C187212893 @default.
• W2005471831 hasConceptScore W2005471831C199343813 @default.
• W2005471831 hasConceptScore W2005471831C2777084678 @default.
• W2005471831 hasConceptScore W2005471831C2778257484 @default.
• W2005471831 hasConceptScore W2005471831C2778560704 @default.
• W2005471831 hasConceptScore W2005471831C2780576314 @default.
• W2005471831 hasConceptScore W2005471831C2986805488 @default.
• W2005471831 hasConceptScore W2005471831C61511704 @default.
• W2005471831 hasConceptScore W2005471831C71924100 @default.
• W2005471831 hasIssue "12" @default.
• W2005471831 hasLocation W20054718311 @default.
• W2005471831 hasLocation W20054718312 @default.
• W2005471831 hasLocation W20054718313 @default.
• W2005471831 hasLocation W20054718314 @default.
• W2005471831 hasOpenAccess W2005471831 @default.
• W2005471831 hasPrimaryLocation W20054718311 @default.
• W2005471831 hasRelatedWork W1585996547 @default.
• W2005471831 hasRelatedWork W2005853978 @default.
• W2005471831 hasRelatedWork W2025510472 @default.
• W2005471831 hasRelatedWork W2057506185 @default.
• W2005471831 hasRelatedWork W2081326938 @default.
• W2005471831 hasRelatedWork W2107008313 @default.
• W2005471831 hasRelatedWork W2388594945 @default.
• W2005471831 hasRelatedWork W2464628730 @default.
• W2005471831 hasRelatedWork W2784036733 @default.
• W2005471831 hasRelatedWork W3022571276 @default.
• W2005471831 hasVolume "82" @default.
• W2005471831 isParatext "false" @default.
• W2005471831 isRetracted "false" @default.
• W2005471831 magId "2005471831" @default.
• W2005471831 workType "article" @default.