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- W2005476256 abstract "Sterigmatocystin, a mycotoxin which is carcinogenic when given orally to rats, was tested for its carcinogenic effects on rat skin. The shaved skin of rats was treated with 1 mg of sterigmatocystin in dimethyl sulfoxide or in acetone twice weekly for 70 weeks. At 40 weeks papillomas developed, and by 70 weeks all treated rats had either papillomas or squamous cell carcinomas. In 17 out of the 20 rats treated with sterigmatocystin, liver lesions, consisting of regenerative changes or hepatocellular carcinomas, were present. The observation that sterigmatocystin is carcinogenic to rat skin emphasizes the danger of skin contamination to laboratory workers." @default.
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- W2005476256 date "1973-10-01" @default.
- W2005476256 modified "2023-10-15" @default.
- W2005476256 title "Carcinogenicity of sterigmatocystin to rat skin" @default.
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- W2005476256 doi "https://doi.org/10.1016/0041-008x(73)90262-7" @default.
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